2-Furancarboxamide, N-(3-methoxyphenyl)-5-(phenylthio)-

Base Information

Chemical Name:2-Furancarboxamide, N-(3-methoxyphenyl)-5-(phenylthio)-
CAS No.:779327-15-0
Molecular Formula:C18H15NO3S
Molecular Weight:325.388
Hs Code.:
DSSTox Substance ID:DTXSID10471525
Wikidata:Q82300050

Synonyms:2-Furancarboxamide, N-(3-methoxyphenyl)-5-(phenylthio)-;779327-15-0;SCHEMBL6427088;DTXSID10471525;N-(3-methoxyphenyl)-5-phenylsulfanyl-furan-2-carboxamide

Suppliers and Price of 2-Furancarboxamide, N-(3-methoxyphenyl)-5-(phenylthio)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Furancarboxamide, N-(3-methoxyphenyl)-5-(phenylthio)-

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:325.07726451
Heavy Atom Count:23
Complexity:387

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)NC(=O)C2=CC=C(O2)SC3=CC=CC=C3

Technology Process of 2-Furancarboxamide, N-(3-methoxyphenyl)-5-(phenylthio)-

There total 3 articles about 2-Furancarboxamide, N-(3-methoxyphenyl)-5-(phenylthio)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 108-98-5
thiophenol

: 75991-00-3
5-bromofuran-2-carboxylic acid (3-methoxyphenyl)amide

: 779327-15-0
5-phenylsulfanylfuran-2-carboxylic acid (3-methoxyphenyl)amide

Guidance literature:: thiophenol; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.25h;

5-bromofuran-2-carboxylic acid (3-methoxyphenyl)amide; In N,N-dimethyl-formamide; at 150 ℃; for 12h;
DOI:10.1021/jm049972y

Reference yield:

: 585-70-6
5-bromo-furan-2-carboxylic acid

: 779327-15-0
5-phenylsulfanylfuran-2-carboxylic acid (3-methoxyphenyl)amide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 78 percent / 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide*HCl; 4-(N,N-dimethylamino)pyridine / dimethylformamide / 14 h / 25 °C

2.1: NaH / dimethylformamide / 0.25 h / 0 °C

2.2: 80 percent / dimethylformamide / 12 h / 150 °C

With dmap; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide;
DOI:10.1021/jm049972y

Reference yield:

: 536-90-3,918666-97-4
m-Anisidine

: 779327-15-0
5-phenylsulfanylfuran-2-carboxylic acid (3-methoxyphenyl)amide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 78 percent / 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide*HCl; 4-(N,N-dimethylamino)pyridine / dimethylformamide / 14 h / 25 °C

2.1: NaH / dimethylformamide / 0.25 h / 0 °C

2.2: 80 percent / dimethylformamide / 12 h / 150 °C

With dmap; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide;
DOI:10.1021/jm049972y