1-benzofuran-2-yl(4-bromophenyl)methanone

Base Information

• Chemical Name: 1-benzofuran-2-yl(4-bromophenyl)methanone
• CAS No.: 29555-25-7
• Molecular Formula: C15H9 Br O2
• Molecular Weight: 301.139
• Hs Code.: 2932999099
• Mol file: 29555-25-7.mol

Synonyms:Ketone,2-benzofuranyl p-bromophenyl (6CI,8CI)

Chemical Property of 1-benzofuran-2-yl(4-bromophenyl)methanone

Chemical Property:

• Vapor Pressure: 6.71E-07mmHg at 25°C
• Melting Point: 151 °C(Solv: cyclohexane (110-82-7))
• Boiling Point: 409°Cat760mmHg
• Flash Point: 201.2°C
• PSA: 30.21000
• Density: 1.5g/cm³
• LogP: 4.42630

Purity/Quality:

1-BENZOFURAN-2-YL(4-BROMOPHENYL)METHANONE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-benzofuran-2-yl(4-bromophenyl)methanone

There total 11 articles about 1-benzofuran-2-yl(4-bromophenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

salicylaldehyde (90-02-8) + para-bromophenacyl bromide (99-73-0,132309-76-3) → benzo[b]furan-2-yl-(4-bromophenyl)-methanone (29555-25-7)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃;

DOI:10.1016/j.bioorg.2020.104238

Reference yield: 88.0%

→ benzo[b]furan-2-yl-(4-bromophenyl)-methanone (29555-25-7)

Guidance literature:

With (phthalocyaninato)iron(II); potassium carbonate; In tetrahydrofuran; at 100 ℃; for 18h; Schlenk technique;

Reference yield: 78.0%

(4-bromo-phenyl)-(3-hydroxy-2,3-dihydro-benzofuran-2-yl)-methanone (27038-01-3,27038-30-8) → benzo[b]furan-2-yl-(4-bromophenyl)-methanone (29555-25-7)

Guidance literature:

With toluene-4-sulfonic acid; at 20 ℃; for 16h; Milling;

DOI:10.1039/c6ob00351f

upstream raw materials:

salicylaldehyde

para-bromophenacyl bromide

(E)-1-(4-bromophenyl)-3-(2-hydroxyphenyl)prop-2-en-1-one

para-bromoacetophenone

Downstream raw materials:

benzofuran-2-yl(4-bromophenyl)methanol

benzo[b]furan-2-yl-(4'-chlorobiphenyl-4-yl)-methanone

[1,1′-biphenyl]-4-yl(benzofuran-2-yl)methanone

[1,1′-biphenyl]-4-yl(benzofuran-2-yl)methanol