1-{[3-(3-Aminopropoxy)phenyl]methyl}piperidin-4-OL

Base Information

Chemical Name:1-{[3-(3-Aminopropoxy)phenyl]methyl}piperidin-4-OL
CAS No.:78057-54-2
Molecular Formula:C₁₅H₂₄N₂O₂
Molecular Weight:264.368
Hs Code.:
DSSTox Substance ID:DTXSID70538360
Wikidata:Q82413715

Synonyms:78057-54-2;SCHEMBL10665231;DTXSID70538360;SGZCKFRHOLSKCZ-UHFFFAOYSA-N;1-{[3-(3-AMINOPROPOXY)PHENYL]METHYL}PIPERIDIN-4-OL;3-[3-[1-(4-hydroxypiperidinyl)methyl]phenoxy]propanamine

Suppliers and Price of 1-{[3-(3-Aminopropoxy)phenyl]methyl}piperidin-4-OL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 1-{[3-(3-Aminopropoxy)phenyl]methyl}piperidin-4-OL

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:264.183778013
Heavy Atom Count:19
Complexity:242

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1O)CC2=CC(=CC=C2)OCCCN

Technology Process of 1-{[3-(3-Aminopropoxy)phenyl]methyl}piperidin-4-OL

There total 2 articles about 1-{[3-(3-Aminopropoxy)phenyl]methyl}piperidin-4-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5382-16-1
4-HYDROXYPIPERIDINE

: 73278-89-4
N'-cyano-N-[3-[3-(1,3-dioxolan-2-yl)phenoxy]propyl]-1-methyl-2-(phenylmethylene) hydrazine carboximidamide

: 78057-54-2
3-[3-[1-(4-hydroxypiperidinyl)methyl]phenoxy] propanamine

Guidance literature:

Reference yield:

: 78057-54-2
3-[3-[1-(4-hydroxypiperidinyl)methyl]phenoxy] propanamine

Guidance literature:

Reference yield:

: 78057-54-2
3-[3-[1-(4-hydroxypiperidinyl)methyl]phenoxy] propanamine

: N-[3-{3-(4-hydroxypiperidinomethyl)phenoxy}propyl]-2-(furfurylthio)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride / CH₂Cl₂ / 12 h / Ambient temperature

2: K₂CO₃, KI / acetonitrile / Heating

With potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; potassium iodide; In dichloromethane; acetonitrile;
DOI:10.1248/cpb.46.610