2-methyl-3-oxo-N-phenethyl-butyramide

Base Information

Chemical Name:2-methyl-3-oxo-N-phenethyl-butyramide
CAS No.:780771-37-1
Molecular Formula:C13H17NO2
Molecular Weight:219.283
Hs Code.:
DSSTox Substance ID:DTXSID40475192

Synonyms:2-methyl-3-oxo-N-phenethyl-butyramide;780771-37-1;SCHEMBL3385526;DTXSID40475192;CXJXEKYPWSMILM-UHFFFAOYSA-N

Suppliers and Price of 2-methyl-3-oxo-N-phenethyl-butyramide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-methyl-3-oxo-N-phenethyl-butyramide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:219.125928785
Heavy Atom Count:16
Complexity:244

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)C)C(=O)NCCC1=CC=CC=C1

Technology Process of 2-methyl-3-oxo-N-phenethyl-butyramide

There total 6 articles about 2-methyl-3-oxo-N-phenethyl-butyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 780771-36-0
2-(2-methyl-1,3-dioxolan-2-yl)-N-phenethylpropionamide

: 780771-37-1
2-methyl-3-oxo-N-phenethylbutyramide

Guidance literature:: With water; toluene-4-sulfonic acid; In acetone; at 20 - 95 ℃;

Reference yield:

: 64-04-0
phenethylamine

: 780771-37-1
2-methyl-3-oxo-N-phenethylbutyramide

Guidance literature:: In 1,2-dimethoxyethane; ethanol; at 180 ℃; for 0.333333h; Microwave irradiation;
DOI:10.1021/ol100624p

Reference yield:

: 609-14-3
2-acetylpropanoic acid ethyl ester

: 780771-37-1
2-methyl-3-oxo-N-phenethylbutyramide

Guidance literature:: Multi-step reaction with 5 steps

1: TsOH*H₂O / toluene / Heating

2: aq. KOH / dioxane / 12 h / 35 °C

3: oxalyl chloride / CH₂Cl₂ / 2 h / 20 °C

4: pyridine / 12 h / 20 °C

5: aq. TsOH / acetone / 3 h / 95 °C

With pyridine; potassium hydroxide; oxalyl dichloride; toluene-4-sulfonic acid; In 1,4-dioxane; dichloromethane; acetone; toluene;
DOI:10.1016/j.bmcl.2005.03.054