Thiophene, 3-[(1E)-2-phenylethenyl]-

Base Information

• Chemical Name: Thiophene, 3-[(1E)-2-phenylethenyl]-
• CAS No.: 78347-97-4
• Molecular Formula: C12H10S
• Molecular Weight: 186.277
• Mol file: 78347-97-4.mol

Synonyms:trans-3-styrylthiophene;(E)-3-(2-phenylethenyl)thiophene;3-styryl-thiophene;3-((E)-Styryl)-thiophene;trans-Phenyl-β-thienylethylen;trans-3-(β-phenylvinyl)thiophene;3-(trans-2-phenylethenyl)thiophen;

Chemical Property of Thiophene, 3-[(1E)-2-phenylethenyl]-

Chemical Property:

• PSA: 28.24000
• LogP: 3.91850

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Thiophene, 3-[(1E)-2-phenylethenyl]-

There total 36 articles about Thiophene, 3-[(1E)-2-phenylethenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-thiophene carboxaldehyde (498-62-4) + O,O-diethyl benzylphosphonate (1080-32-6) → (E)-3-styrylthiophene (78347-97-4)

Guidance literature:

With sodium methylate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1.75h;

Reference yield: 96.0%

3-Bromothiophene (872-31-1) + styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → (E)-3-styrylthiophene (78347-97-4)

Guidance literature:

With potassium carbonate; In water; dimethyl sulfoxide; at 90 ℃; for 10h; Green chemistry;

DOI:10.1039/c4gc00412d

Reference yield: 92.0%

1-phenyl-2-(3-thienyl)ethyne (131423-29-5) → (E)-3-styrylthiophene (78347-97-4)

Guidance literature:

With water; potassium ethyl xanthogenate; In N,N-dimethyl-formamide; at 130 ℃; for 12h; stereoselective reaction; Schlenk technique;

DOI:10.1039/C9CC00128J

upstream raw materials:

3-thiophene carboxaldehyde

O,O-diethyl benzylphosphonate

N,N-dimethyl-formamide

4-bromo-3-(trans-2-phenylethenyl)thiophen

Downstream raw materials:

3-(2-phenylethyl)thiophene

(Z)-3-(2-phenylethenyl)thiophene

3-thiophene carboxaldehyde

benzaldehyde