2-acetyl-1H-indole-3-carboxylic Acid

Base Information

Chemical Name:2-acetyl-1H-indole-3-carboxylic Acid
CAS No.:78839-04-0
Molecular Formula:C₁₁H₉NO₃
Molecular Weight:203.197
Hs Code.:2933990090
European Community (EC) Number:819-143-2
DSSTox Substance ID:DTXSID80392031

Synonyms:2-acetyl-1H-indole-3-carboxylic Acid;78839-04-0;2-acetylindole-3-carboxylic;SCHEMBL16433366;DTXSID80392031;MFCD01449989;2-acetyl-1H-indole-3-carboxylicAcid;AKOS002124963;CS-0236043;EN300-1667080;SR-01000102642;SR-01000102642-1;Z1508931475

Suppliers and Price of 2-acetyl-1H-indole-3-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
2-Acetyl-1H-indole-3-carboxylicacid
500mg
$ 1477.00

Total 5 raw suppliers

Chemical Property of 2-acetyl-1H-indole-3-carboxylic Acid

Chemical Property:

PSA：70.16000
LogP:2.06870
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:203.058243149
Heavy Atom Count:15
Complexity:290

Purity/Quality:

99% ^*data from raw suppliers

2-Acetyl-1H-indole-3-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=C(C2=CC=CC=C2N1)C(=O)O

Technology Process of 2-acetyl-1H-indole-3-carboxylic Acid

There total 1 articles about 2-acetyl-1H-indole-3-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 70097-14-2
1-(2-oxopropyl)indole-2,3-dione

: 78839-04-0
2-acetylindole-3-carboxylic acid

Guidance literature:: With sodium hydroxide; In water; at 20 ℃; for 1.16667h;
DOI:10.1007/BF00515352

Reference yield:

: 78839-04-0
2-acetylindole-3-carboxylic acid

: 2-[2-hydroxy-3-(4-phenylpiperazino)propyl]-4,5-dimethyl-2,5-dihydro-1H-pyrid-azino[4,5-b]indol-1-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

2.1: hydrazine hydrate / ethanol / 24 h / Reflux

3.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 20 °C

3.2: 72 h / 60 °C

4.1: tetrahydrofuran / 24 h / Reflux

With sodium hydride; potassium carbonate; hydrazine hydrate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
DOI:10.3998/ark.5550190.p009.763

Reference yield:

: 78839-04-0
2-acetylindole-3-carboxylic acid

: N-benzyl-N-(4,5-dimethyl-5H-pyridazino[4,5-b]indol-1-yl)amine

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

2: hydrazine hydrate / ethanol / 24 h / Reflux

3: trichlorophosphate / 4 h / 100 °C

4: 20 h / 170 °C

With potassium carbonate; hydrazine hydrate; trichlorophosphate; In ethanol; N,N-dimethyl-formamide;
DOI:10.3998/ark.5550190.p009.763