Ethyl 2-amino-4-tert-butyl-1,3-thiazole-5-carboxylate

Base Information

Chemical Name:Ethyl 2-amino-4-tert-butyl-1,3-thiazole-5-carboxylate
CAS No.:78968-26-0
Molecular Formula:C₁₀H₁₆N₂O₂S
Molecular Weight:228.315
Hs Code.:
DSSTox Substance ID:DTXSID60356439
Wikidata:Q82135767
ChEMBL ID:CHEMBL1532582
Mol file:78968-26-0.mol

Synonyms:ethyl 2-amino-4-tert-butyl-1,3-thiazole-5-carboxylate;78968-26-0;SMR000162678;Oprea1_152635;MLS000545687;SCHEMBL289519;CHEMBL1532582;DTXSID60356439;HMS2305L03;MFCD00665917;STL131920;AKOS005739171;CS-0455810;FT-0723599;EN300-6509930;AB-601/30965049;Ethyl 2-amino-4-(tert-butyl)thiazole-5-carboxylate

Suppliers and Price of Ethyl 2-amino-4-tert-butyl-1,3-thiazole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-AMINO-4-(1,1-DIMETHYLETHYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER 95.00%
5MG
$ 496.91

Total 1 raw suppliers

Chemical Property of Ethyl 2-amino-4-tert-butyl-1,3-thiazole-5-carboxylate

Chemical Property:

PSA：94.18000
LogP:2.12960
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:228.09324893
Heavy Atom Count:15
Complexity:240

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

2-AMINO-4-(1,1-DIMETHYLETHYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(N=C(S1)N)C(C)(C)C

Technology Process of Ethyl 2-amino-4-tert-butyl-1,3-thiazole-5-carboxylate

There total 5 articles about Ethyl 2-amino-4-tert-butyl-1,3-thiazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 29509-07-7
2-chloro-4,4-dimethyl-3-oxopentanoic acid ethyl ester

: 17356-08-0
thiourea

: 78968-26-0
ethyl 2-amino-4-tert-butyl-1,3-thiazole-5-carboxylate

Guidance literature:: In ethanol; for 16h; Heating;

Reference yield:

: 17094-34-7
ethyl pivaloylacetate

: 78968-26-0
ethyl 2-amino-4-tert-butyl-1,3-thiazole-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 25.6 g / Br₂ / H₂O / 0.5 h / 0 °C

2: 22 g / ethanol / 1 h / Heating

With bromine; In ethanol; water;