2-Bromo-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one

Base Information

• Chemical Name: 2-Bromo-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one
• CAS No.: 79174-57-5
• Molecular Formula: C10H7BrClN3O
• Molecular Weight: 300.542
• DSSTox Substance ID: DTXSID40513063

Synonyms:79174-57-5;DTXSID40513063;2-Bromo-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one

Chemical Property of 2-Bromo-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one

Chemical Property:

• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 298.94610
• Heavy Atom Count: 16
• Complexity: 258

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(=O)C(N2C=NC=N2)Br)Cl

Technology Process of 2-Bromo-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one

There total 2 articles about 2-Bromo-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone (58905-19-4) → ω-bromo-ω-(1,2,4-triazol-1-yl)-4-chloroacetophenone (79174-57-5)

Guidance literature:

With bromine; sodium acetate; In acetic acid;

Reference yield:

4-chlorobenzoylmethyl bromide (536-38-9) → ω-bromo-ω-(1,2,4-triazol-1-yl)-4-chloroacetophenone (79174-57-5)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / acetone

2: bromine; sodium acetate / acetic acid

With bromine; sodium acetate; triethylamine; In acetic acid; acetone;

DOI:10.1080/10426507.2010.497519

Reference yield: 90.0%

ω-bromo-ω-(1,2,4-triazol-1-yl)-4-chloroacetophenone (79174-57-5) + amino[3-phenyl-5-(2-thienyl)(2-pyrazolinyl)]methane-1-thione (29338-66-7) → C26H19ClN6S (1278594-46-9)

Guidance literature:

In ethanol; for 0.5h; Reflux;

DOI:10.1080/10426507.2010.497519

upstream raw materials:

1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone

4-chlorobenzoylmethyl bromide

Downstream raw materials:

3-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)-2H-benzo[b][1,4]thiazine

C₂₆H₁₇Cl₃N₆S

C₂₇H₂₀Cl₂N₆OS

C₂₆H₁₉ClN₆S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 79174-57-5 Ethanone, 2-bromo-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send