(2-(4-chlorophenoxy)phenyl)MethanaMine

Base Information

• Chemical Name: (2-(4-chlorophenoxy)phenyl)MethanaMine
• CAS No.: 792158-57-7
• Molecular Formula: C13H12ClNO
• Molecular Weight: 233.697
• Hs Code.: 2922190090
• DSSTox Substance ID: DTXSID70601341
• Wikidata: Q82497938
• Mol file: 792158-57-7.mol

Synonyms:792158-57-7;(2-(4-chlorophenoxy)phenyl)MethanaMine;2-(4-Chlorophenoxy)-benzylamine;Benzenemethanamine, 2-(4-chlorophenoxy)-;[2-(4-chlorophenoxy)phenyl]methanamine;2-(4-chlorophenoxy)benzylamine;1-[2-(4-Chlorophenoxy)phenyl]methanamine;SCHEMBL641336;DTXSID70601341;IAXVDWCOADTYIX-UHFFFAOYSA-N;MFCD11191890;SB77112;AS-81839;DB-234641;CS-0455828;F20141;A1-08789

Chemical Property of (2-(4-chlorophenoxy)phenyl)MethanaMine

Chemical Property:

• PSA: 35.25000
• LogP: 4.29130
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 233.0607417
• Heavy Atom Count: 16
• Complexity: 204

Purity/Quality:

95%-98% ^*data from raw suppliers

2-(4-Chlorophenoxy)-benzylamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)CN)OC2=CC=C(C=C2)Cl

Technology Process of (2-(4-chlorophenoxy)phenyl)MethanaMine

There total 1 articles about (2-(4-chlorophenoxy)phenyl)MethanaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-(4-chlorophenoxy)-benzonitrile (146537-85-1) → 2-(4-chlorophenoxy)benzenemethanamine (792158-57-7)

Guidance literature:

2-(4-chlorophenoxy)-benzonitrile; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

With water; ammonium chloride; In tetrahydrofuran; Cooling;

Reference yield: 84.0%

2-(4-chlorophenoxy)benzenemethanamine (792158-57-7) + 1-Benzoyl-4-piperidone (24686-78-0) → {4-[2-(4-chlorophenoxy)benzylamino]piperidin-1-yl}phenylmethanone

Guidance literature:

2-(4-chlorophenoxy)benzenemethanamine; 1-Benzoyl-4-piperidone; With sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 0.5h;

With water; sodium hydrogencarbonate; In 1,2-dichloro-ethane;

Reference yield: 81.0%

2-(4-chlorophenoxy)benzenemethanamine (792158-57-7) + 1-cyclopentanecarbonylpiperidin-4-one (919118-54-0) → {4-[2-(4-chlorophenoxy)benzylamino]piperidin-1-yl}cyclopentylmethanone

Guidance literature:

2-(4-chlorophenoxy)benzenemethanamine; 1-cyclopentanecarbonylpiperidin-4-one; With sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 0.5h;

With water; sodium hydrogencarbonate; In 1,2-dichloro-ethane;

upstream raw materials:

2-(4-chlorophenoxy)-benzonitrile

Refernces