1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)-

Base Information

Chemical Name:1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)-
CAS No.:796095-60-8
Molecular Formula:C11H19NO5
Molecular Weight:245.276
Hs Code.:

Synonyms:cis-4-hydroxy-N-tert-butoxycarbonyl-L-proline methyl ester;4-hydroxypyrrolidine-1,2-dicarboxylic acid-1-tert-butylester 2-methylester;1-tert-butyl 2-methyl (2S)-4-hydroxypyrrolidin-1,2-dicarboxylate;methyl 1-(tert-butoxycarbonyl)-4-hydroxyproline;4-hydroxypyrrolidine-1,2-dicarboxylic acid-1-tert-butyl ester 2-methyl ester;4-hydroxypyrrolidine-1,2-dicarboxylic acid-1-tert-butylester-2-methylester;1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl)2-methyl ester, (2S)-;

Suppliers and Price of 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)-

Chemical Property:

PSA：76.07000
LogP:0.46760

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)-

There total 1 articles about 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34619-03-9
tert-butyldicarbonate

: 40126-30-5,40216-83-9,114676-59-4,116839-10-2
(S)-4-Hydroxy-pyrrolidine-2-carboxylic acid methyl ester, hydrochloride

: 796095-60-8
(2S)-1-tert-butoxycarbonyl-2-(methoxycarbonyl)-4-hydroxyazacyclopentane

Guidance literature:: With sodium hydrogencarbonate; In 1,4-dioxane;

Reference yield: 32.0%

: 796095-60-8
(2S)-1-tert-butoxycarbonyl-2-(methoxycarbonyl)-4-hydroxyazacyclopentane

: 98-59-9
p-toluenesulfonyl chloride

: tert-butyl (2S)-2-methoxycarbonyl-4-p-toluenesulfonyloxypyrrolidine-1-carboxylate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 6h; Inert atmosphere;

Reference yield: 27.0%

: 796095-60-8
(2S)-1-tert-butoxycarbonyl-2-(methoxycarbonyl)-4-hydroxyazacyclopentane

: 6315-52-2
1,2-bis-tosyloxyethane

: 1-tert-butyl 2-methyl 4-[2-(toluene-4-sulfonyloxy)ethoxy]pyrrolidine-1,2-dicarboxylate

Guidance literature:: (2S)-1-tert-butoxycarbonyl-2-(methoxycarbonyl)-4-hydroxyazacyclopentane; With sodium hydride; In N,N-dimethyl-formamide; for 0.25h;

1,2-bis-tosyloxyethane; In N,N-dimethyl-formamide; at 100 ℃; for 0.75h; Microwave irradiation;