N~2~-(Benzenesulfonyl)-N~2~-(3-chloro-4-methoxyphenyl)-N-[(2-methoxyphenyl)methyl]glycinamide

Base Information

Chemical Name:N~2~-(Benzenesulfonyl)-N~2~-(3-chloro-4-methoxyphenyl)-N-[(2-methoxyphenyl)methyl]glycinamide
CAS No.:5869-43-2
Molecular Formula:C₁₆H₂₀O₃
Molecular Weight:260.333
Hs Code.:
DSSTox Substance ID:DTXSID00360595
Wikidata:Q82142414

Synonyms:5869-43-2;CBMicro_036007;Oprea1_371611;Oprea1_376128;DTXSID00360595;STL199818;AKOS000386149;BIM-0035848.P001;N~2~-(3-chloro-4-methoxyphenyl)-N-(2-methoxybenzyl)-N~2~-(phenylsulfonyl)glycinamide;N~2~-(Benzenesulfonyl)-N~2~-(3-chloro-4-methoxyphenyl)-N-[(2-methoxyphenyl)methyl]glycinamide

Suppliers and Price of N~2~-(Benzenesulfonyl)-N~2~-(3-chloro-4-methoxyphenyl)-N-[(2-methoxyphenyl)methyl]glycinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N~2~-(Benzenesulfonyl)-N~2~-(3-chloro-4-methoxyphenyl)-N-[(2-methoxyphenyl)methyl]glycinamide

Chemical Property:

Density:1.331g/cm³
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:474.1016207
Heavy Atom Count:32
Complexity:695

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)N(CC(=O)NCC2=CC=CC=C2OC)S(=O)(=O)C3=CC=CC=C3)Cl

Technology Process of N~2~-(Benzenesulfonyl)-N~2~-(3-chloro-4-methoxyphenyl)-N-[(2-methoxyphenyl)methyl]glycinamide

There total 4 articles about N~2~-(Benzenesulfonyl)-N~2~-(3-chloro-4-methoxyphenyl)-N-[(2-methoxyphenyl)methyl]glycinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6'.7'-Dimethoxy-1'.4'.4'aα,9'.10'.10'aβ-hexahydrospiro<1.3-dioxolan-2.3'(2'H)-phenanthren>

: 5869-43-2
6,7-Dimethoxy-1,4,4aα,9,10,10aβ-hexahydro-3(2H)-phenanthrenon

Guidance literature:: With hydrogenchloride; In methanol;
DOI:10.1021/jm00321a009

Reference yield:

: 6'.7'-Dimethoxy-1'.4'.4'aβ,9'.10'.10'aβ-hexahydrospiro<1.3-dioxolan-2.3'(2'H)-phenanthren>

: 5869-43-2
1,4,4aβ,9,10,10aβ-Hexahydro-6,7-dimethoxy-3(2H)-phenanthrenon

Guidance literature:: With hydrogenchloride; In methanol;
DOI:10.1021/jm00321a009

Reference yield:

: 5869-10-3
6'.7'-Dimethoxy-1'.4'.9'.10'-tetrahydrospiro<1.3-dioxolan-2'.3'(2'H)-phenanthren>

: 5869-43-2
6,7-Dimethoxy-1,4,4aα,9,10,10aβ-hexahydro-3(2H)-phenanthrenon

Guidance literature:: Multi-step reaction with 2 steps

1: (i) K, liq. NH₃, THF, (ii) aq. HCl

2: aq. NaOH

With sodium hydroxide;
DOI:10.1021/jm00321a009