3-Pyrrolidineacetamide, N-hydroxy-2-oxo-1-(phenylmethyl)-

Base Information

Chemical Name:3-Pyrrolidineacetamide, N-hydroxy-2-oxo-1-(phenylmethyl)-
CAS No.:798543-04-1
Molecular Formula:C13H16N2O3
Molecular Weight:248.282
Hs Code.:
DSSTox Substance ID:DTXSID40460568

Synonyms:798543-04-1;3-Pyrrolidineacetamide, N-hydroxy-2-oxo-1-(phenylmethyl)-;SCHEMBL2566621;2-(1-benzyl-2-oxo-pyrrolidin-3-yl)-N-hydroxy-acetamide;DTXSID40460568;FJKREPIGQPRVNT-UHFFFAOYSA-N;2-(1-BENZYL-2-OXOPYRROLIDIN-3-YL)-N-HYDROXYACETAMIDE

Suppliers and Price of 3-Pyrrolidineacetamide, N-hydroxy-2-oxo-1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Pyrrolidineacetamide, N-hydroxy-2-oxo-1-(phenylmethyl)-

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:248.11609238
Heavy Atom Count:18
Complexity:313

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C(=O)C1CC(=O)NO)CC2=CC=CC=C2

Technology Process of 3-Pyrrolidineacetamide, N-hydroxy-2-oxo-1-(phenylmethyl)-

There total 4 articles about 3-Pyrrolidineacetamide, N-hydroxy-2-oxo-1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

: 61006-66-4
(1-benzyl-2-oxo-pyrrolidin-3-yl)-acetic acid methyl ester

: 798543-04-1
2-(1-benzyl-2-oxo-pyrrolidin-3-yl)-N-hydroxy-acetamide

Guidance literature:: With hydroxylamine potassium salt; In methanol; at 0 - 20 ℃; for 4h;

Reference yield:

: 4383-22-6
Allylbenzylamine

: 798543-04-1
2-(1-benzyl-2-oxo-pyrrolidin-3-yl)-N-hydroxy-acetamide

Guidance literature:: Multi-step reaction with 4 steps

1: dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane / 10 h / 20 °C

2: Grubbs catalyst first generation / dichloromethane / 24 h / 20 °C

3: hydrogen / palladium on activated charcoal / methanol / 1 - 2 h / 20 °C

4: hydroxylamine potassium salt / methanol / 4 h / 0 - 20 °C

With dmap; hydroxylamine potassium salt; hydrogen; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; Grubbs catalyst first generation; palladium on activated charcoal; In methanol; dichloromethane;

Reference yield:

: 798542-99-1
(1-benzyl-2-oxo-2,5-dihydro-1H-pyrrol-3-yl)-acetic acid methyl ester

: 798543-04-1
2-(1-benzyl-2-oxo-pyrrolidin-3-yl)-N-hydroxy-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / palladium on activated charcoal / methanol / 1 - 2 h / 20 °C

2: hydroxylamine potassium salt / methanol / 4 h / 0 - 20 °C

With hydroxylamine potassium salt; hydrogen; palladium on activated charcoal; In methanol;