4-[2-(1H-1,2,4-triazol-1-yl)ethyl]phenol

Base Information

Chemical Name:4-[2-(1H-1,2,4-triazol-1-yl)ethyl]phenol
CAS No.:80200-08-4
Molecular Formula:C10H11N3O
Molecular Weight:189.217
Hs Code.:
DSSTox Substance ID:DTXSID00603535
Wikidata:Q82500972

Synonyms:4-[2-(1H-1,2,4-triazol-1-yl)ethyl]phenol;80200-08-4;SCHEMBL10786317;DTXSID00603535;MWDMJNPTVJKNGD-UHFFFAOYSA-N;4-[2-(1H-1,2,4,-triazol-1-yl)ethyl]phenol

Suppliers and Price of 4-[2-(1H-1,2,4-triazol-1-yl)ethyl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-[2-(1H-1,2,4-triazol-1-yl)ethyl]phenol

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:189.090211983
Heavy Atom Count:14
Complexity:169

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CCN2C=NC=N2)O

Technology Process of 4-[2-(1H-1,2,4-triazol-1-yl)ethyl]phenol

There total 3 articles about 4-[2-(1H-1,2,4-triazol-1-yl)ethyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 88670-73-9
1-[2-(4-Benzyloxy-phenyl)-ethyl]-1H-[1,2,4]triazole

: 80200-08-4
4-[2-(1H-1,2,4-triazol-1-yl)ethyl]phenol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr; Ambient temperature;
DOI:10.1021/jm00370a012

Reference yield:

: 61439-60-9
1-benzyloxy-4-(2-methanesulfonyloxyethyl)benzene

: 80200-08-4
4-[2-(1H-1,2,4-triazol-1-yl)ethyl]phenol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) sodium hydride / 1.) DMF, 5 min, 2.) DMF, 60 deg C, 30 min

2: 85 percent / H₂ / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature

With hydrogen; sodium hydride; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00370a012