Cytochalasin G

Base Information

Chemical Name:Cytochalasin G
CAS No.:70852-29-8
Molecular Formula:C29H34N2O4
Molecular Weight:474.5913
Hs Code.:
Wikidata:Q105348133

Synonyms:Cytochalasin G;3H-Cycloundec(d)oxireno(f)isoindole-6,9,10(11H)-trione,4,5,7,8,12,12a,13,13a,14a,14b-decahydro-12-(1H-indol-3-ylmethyl)-4,13,13a-trimethyl-, (1E,4S,9aR,12S,12aR,13S,13aR,14aS,14bR)-;70852-29-8;SCHEMBL33536;C29H34N2O4;C29-H34-N2-O4

Suppliers and Price of Cytochalasin G

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of Cytochalasin G

Chemical Property:

Vapor Pressure:3.18E-21mmHg at 25°C
Boiling Point:730.9°Cat760mmHg
Flash Point:395.9°C
PSA：95.05000
Density:1.27g/cm³
LogP:4.41520
XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:474.25185757
Heavy Atom Count:35
Complexity:947

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC=CC2C3C(O3)(C(C4C2(C(=O)CCC(=O)C1)C(=O)NC4CC5=CNC6=CC=CC=C65)C)C
Isomeric SMILES:C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@@]2(C(=O)CCC(=O)C1)C(=O)N[C@H]4CC5=CNC6=CC=CC=C65)C)C

Technology Process of Cytochalasin G

There total 22 articles about Cytochalasin G which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 122768-73-4
(6R,7S,16S)-2-benzoyl-10-(1-benzoylindol-3-yl)-6,7-epoxy-16-methyl<11>cytochalas-13^t-ene-1,18,21-trione

: 70852-29-8
cytochalasin G

Guidance literature:: With sodium hydroxide; In methanol; water; for 16h;

Reference yield:

: 139091-30-8,109364-32-1
(S)-benzyl (1-(indol-3-yl)-3-oxopropan-2-yl)carbamate

: 70852-29-8
cytochalasin G

Guidance literature:: Multi-step reaction with 11 steps

1: 70 percent / LDA

2: 81 percent / H₂, AcOH / Pd/C / ethanol

3: 95 percent / NaOEt / ethanol

4: 77 percent / Et₃N, DMAP

5: 68 percent / LiN(SiMe₃)2

6: 84 percent / LiN(SiMe₃)2

7: H₂O₂, m-chloroperoxybenzoic acid / 1.) -40 deg C, 2.) 0 deg C

8: toluene / 7 h / 80 °C

9: 71 percent / 5percent aq. HCl / tetrahydrofuran

10: 39 percent / m-chloroperoxybenzoic acid

11: 62 percent / NaOH / methanol

With hydrogenchloride; dmap; sodium hydroxide; hydrogen; dihydrogen peroxide; sodium ethanolate; acetic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium hexamethyldisilazane; lithium diisopropyl amide; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; toluene;
DOI:10.1039/c39860001447

Reference yield:

: 2717-76-2,130812-44-1,130812-46-3
(S)-N-benzyloxycarbonyl-L-tryptophan methyl ester

: 70852-29-8
cytochalasin G

Guidance literature:: Multi-step reaction with 12 steps

1: 73 percent / i-Bu₂AlH

2: 70 percent / LDA

3: 81 percent / H₂, AcOH / Pd/C / ethanol

4: 95 percent / NaOEt / ethanol

5: 77 percent / Et₃N, DMAP

6: 68 percent / LiN(SiMe₃)2

7: 84 percent / LiN(SiMe₃)2

8: H₂O₂, m-chloroperoxybenzoic acid / 1.) -40 deg C, 2.) 0 deg C

9: toluene / 7 h / 80 °C

10: 71 percent / 5percent aq. HCl / tetrahydrofuran

11: 39 percent / m-chloroperoxybenzoic acid

12: 62 percent / NaOH / methanol

With hydrogenchloride; dmap; sodium hydroxide; hydrogen; dihydrogen peroxide; sodium ethanolate; diisobutylaluminium hydride; acetic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium hexamethyldisilazane; lithium diisopropyl amide; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; toluene;
DOI:10.1039/c39860001447