5-(4-methoxyphenyl)-4-phenyl-1H-pyrazol-3-amine

Base Information

Chemical Name:5-(4-methoxyphenyl)-4-phenyl-1H-pyrazol-3-amine
CAS No.:802919-04-6
Molecular Formula:C16H15N3O
Molecular Weight:265.315
Hs Code.:
DSSTox Substance ID:DTXSID30458813
Wikidata:Q82282345

Synonyms:802919-04-6;5-(4-methoxyphenyl)-4-phenyl-1H-pyrazol-3-amine;CTK3E5803;SCHEMBL19926114;DTXSID30458813

Suppliers and Price of 5-(4-methoxyphenyl)-4-phenyl-1H-pyrazol-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-(4-methoxyphenyl)-4-phenyl-1H-pyrazol-3-amine

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:265.121512110
Heavy Atom Count:20
Complexity:298

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(C(=NN2)N)C3=CC=CC=C3

Technology Process of 5-(4-methoxyphenyl)-4-phenyl-1H-pyrazol-3-amine

There total 3 articles about 5-(4-methoxyphenyl)-4-phenyl-1H-pyrazol-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: (Z)-3-chloro-3-(4-(methoxy)phenyl)-2-phenylacrylonitrile

: 802919-04-6
5-(4-methoxy-phenyl)-4-phenyl-1H-pyrazol-3-ylamine

Guidance literature:: With hydrazine hydrate; In ethanol; for 18h; Reflux; Schlenk technique; Inert atmosphere;
DOI:10.1002/anie.201705851

Reference yield:

: 5415-11-2
3-(4-methoxyphenyl)-3-oxo-2-phenylpropanenitrile

: 802919-04-6
5-(4-methoxy-phenyl)-4-phenyl-1H-pyrazol-3-ylamine

Guidance literature:: With hydrogenchloride; hydrazine; In ethanol; at 80 ℃; for 8h;
DOI:10.1016/j.bmcl.2004.08.046

Reference yield:

: 140-29-4
phenylacetonitrile

: 802919-04-6
5-(4-methoxy-phenyl)-4-phenyl-1H-pyrazol-3-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran / 48 h / 65 °C

2: hydrazine; HCl / ethanol / 8 h / 80 °C

With hydrogenchloride; sodium hydride; hydrazine; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmcl.2004.08.046