Benzo[b]thiophene-2-carboxylic acid, 4,7-dihydroxy-, methyl ester

Base Information

• Chemical Name: Benzo[b]thiophene-2-carboxylic acid, 4,7-dihydroxy-, methyl ester
• CAS No.: 80427-78-7
• Molecular Formula: C10H8O4S
• Molecular Weight: 224.237
• Mol file: 80427-78-7.mol

Synonyms:

Chemical Property of Benzo[b]thiophene-2-carboxylic acid, 4,7-dihydroxy-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzo[b]thiophene-2-carboxylic acid, 4,7-dihydroxy-, methyl ester

There total 1 articles about Benzo[b]thiophene-2-carboxylic acid, 4,7-dihydroxy-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-formyl-1,4-benzoquinone (26172-03-2) → methyl 4,7-dihydroxybenzothiophene-2-carboxylate (80427-78-7)

Guidance literature:

Multi-step reaction with 3 steps

1: benzene / 24 h / Ambient temperature

2: 97 percent / anhydrous sodium acetate / 1 h / Heating

3: 97 percent / sulphuric acid / methanol / 2 h / Heating

With sulfuric acid; sodium acetate; In methanol; benzene;

Reference yield:

4-trans-pentylcyclohexane-1-carboxylic acid (38289-29-1,38792-89-1,67589-84-8) + methyl 4,7-dihydroxybenzothiophene-2-carboxylate (80427-78-7) → C34H48O6S

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere; Cooling;

upstream raw materials:

2-formyl-1,4-benzoquinone

Refernces