4-(1H-Imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylaniline

Base Information

• Chemical Name: 4-(1H-Imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylaniline
• CAS No.: 80675-86-1
• Molecular Formula: C14H14N4
• Molecular Weight: 238.292
• ChEMBL ID: CHEMBL355818
• DSSTox Substance ID: DTXSID30505699
• Nikkaji Number: J1.202.112G
• Wikidata: Q82360981
• Mol file: 80675-86-1.mol

Synonyms:80675-86-1;4-(1H-Imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylaniline;CHEMBL355818;4-{1H-imidazo[4,5-c]pyridin-2-yl}-N,N-dimethylaniline;CHEMBL394313;SCHEMBL7278198;4-(3H-imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylaniline;DTXSID30505699;BDBM50224739;AKOS006181219;4-(3H-imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylbenzenamine

Chemical Property of 4-(1H-Imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylaniline

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 238.121846464
• Heavy Atom Count: 18
• Complexity: 273

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)C2=NC3=C(N2)C=NC=C3

Technology Process of 4-(1H-Imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylaniline

There total 6 articles about 4-(1H-Imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3,4-diaminopyridine (54-96-6) + 4-dimethylamino-benzaldehyde (100-10-7) → 4-(1H-imidazo[4,5-c]pyridin-2-yl)-N,N-dimethylaniline (80675-86-1)

Guidance literature:

With sulfur; at 165 - 175 ℃; for 3h;

DOI:10.1007/BF00476381

Reference yield: 80.0%

4-amino-3-nitropyridine (1681-37-4) + 4-dimethylamino-benzaldehyde (100-10-7) → 2-(4'-(N,N-dimethylamino)phenyl)imidazo[4,5-c]pyridine (80675-86-1)

Guidance literature:

With sodium dithionite; In ethanol; water; at 80 ℃; for 4h;

DOI:10.1080/00397910903011345

Reference yield:

3,4-diaminopyridine (54-96-6) + 4-dimethylamino-benzaldehyde (100-10-7) → 2-(4'-(N,N-dimethylamino)phenyl)imidazo[4,5-c]pyridine (80675-86-1)

Guidance literature:

With nitrobenzene; at 150 ℃;

DOI:10.1016/j.bmcl.2007.09.076

upstream raw materials:

3,4-diaminopyridine

4-dimethylamino-benzaldehyde

4-amino-3-nitropyridine

p-N,N-dimethylaminobenzoic acid