6-[(4-Aminobutyl)methylamino]phthalazine-1,4(2H,3H)-dione

Base Information

• Chemical Name: 6-[(4-Aminobutyl)methylamino]phthalazine-1,4(2H,3H)-dione
• CAS No.: 80944-69-0
• Molecular Formula: C₁₃H₁₈N₄O₂
• Molecular Weight: 262.312
• Mol file: 80944-69-0.mol

Synonyms:1,4-Phthalazinedione,6-[(4-aminobutyl)methylamino]-2,3-dihydro;6-[(4-Aminobutyl)methylamino]phthalazine-1,4(2H,3H)-dione;

Chemical Property of 6-[(4-Aminobutyl)methylamino]phthalazine-1,4(2H,3H)-dione

Chemical Property:

• PSA: 95.50000
• LogP: 1.91640

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-[(4-Aminobutyl)methylamino]phthalazine-1,4(2H,3H)-dione

There total 2 articles about 6-[(4-Aminobutyl)methylamino]phthalazine-1,4(2H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-{[4-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-methyl-amino}-2-methyl-isoindole-1,3-dione → 6-2,3-dihydro-1,4-phthalazinedione (80944-69-0)

Guidance literature:

With hydrazine; In ethanol; at 85 ℃; for 4h;

DOI:10.1246/bcsj.60.2023

Reference yield:

N-methyl-4-N-<4-(N-phthalimide)butyl>aminophthalimide → 6-2,3-dihydro-1,4-phthalazinedione (80944-69-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 h / 140 °C

2: hydrazine / ethanol / 4 h / 85 °C

With hydrazine; In ethanol;

DOI:10.1246/bcsj.60.2023