2-Methylnaphthalene-1-carbonyl chloride

Base Information

• Chemical Name: 2-Methylnaphthalene-1-carbonyl chloride
• CAS No.: 10008-12-5
• Molecular Formula: C12H9 Cl O
• Molecular Weight: 204.656
• Hs Code.: 2916399090
• European Community (EC) Number: 233-003-2
• DSSTox Substance ID: DTXSID90142923
• Nikkaji Number: J241.217I
• Wikidata: Q83006534
• Mol file: 10008-12-5.mol

Synonyms:2-Methylnaphthalene-1-carbonyl chloride;10008-12-5;EINECS 233-003-2;1-Naphthalenecarbonyl chloride, 2-methyl-;2-methylnaphthoyl chloride;SCHEMBL4033364;DTXSID90142923;AKOS004907837;2-Methyl-naphthalene-1-carbonyl chloride;2-Methyl-1-naphthalenecarboxylic acid chloride

Chemical Property of 2-Methylnaphthalene-1-carbonyl chloride

Chemical Property:

• Vapor Pressure: 0.000262mmHg at 25°C
• Boiling Point: 323.4°Cat760mmHg
• Flash Point: 150.5°C
• PSA: 17.07000
• Density: 1.231g/cm³
• LogP: 3.52720
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 204.0341926
• Heavy Atom Count: 14
• Complexity: 226

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-NAPHTHALENECARBONYL CHLORIDE, 2-METHYL- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C2=CC=CC=C2C=C1)C(=O)Cl

Technology Process of 2-Methylnaphthalene-1-carbonyl chloride

There total 2 articles about 2-Methylnaphthalene-1-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-1-naphthoic acid (1575-96-8) → 2-methyl-1-naphthoyl chloride (10008-12-5)

Guidance literature:

With thionyl chloride;

DOI:10.1021/ja01855a079

Reference yield:

1-bromo-2-methylnaphtalene (2586-62-1) → 2-methyl-1-naphthoyl chloride (10008-12-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) lithium / 1.) ether, 2 h, 2.) ether

2: oxalyl chloride, DMF / toluene / 1 h / 25 °C

With oxalyl dichloride; lithium; N,N-dimethyl-formamide; In toluene;

DOI:10.1021/jm960093o

Reference yield: 82.0%

2-methyl-1-naphthoyl chloride (10008-12-5) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → (2-methylnaphthalen-1-yl)(phenyl)methanone (4919-69-1)

Guidance literature:

DOI:10.1007/s11176-005-0320-0

upstream raw materials:

2-methyl-1-naphthoic acid

1-bromo-2-methylnaphtalene

Downstream raw materials:

biphenyl-4-yl-(2-methyl-[1]naphthyl)-ketone

ethyl 2-methyl-1-naphthalenecarboxylate

10,11-dihydro-9H-benzo[a]cyclopent[i]anthracene

2,3-dihydro-1H-benzo[a]cyclopent[h]anthracene