4-(4-Fluorophenyl)-2-methylbut-3-yn-2-ol

Base Information

Chemical Name:4-(4-Fluorophenyl)-2-methylbut-3-yn-2-ol
CAS No.:81233-93-4
Molecular Formula:C₁₁H₁₁FO
Molecular Weight:178.206
Hs Code.:2906290090
DSSTox Substance ID:DTXSID30409062
Nikkaji Number:J735.206I
Wikidata:Q82214727
Mol file:81233-93-4.mol

Synonyms:4-(4-fluorophenyl)-2-methylbut-3-yn-2-ol;81233-93-4;4-(4-Fluoro-phenyl)-2-methyl-but-3-yn-2-ol;4-{4-fluorophenyl)-2-methylbut-3-yn-2-ol;SCHEMBL700507;DTXSID30409062;DXHAOZOATVEAFG-UHFFFAOYSA-N;AMY15478;FD7200;MFCD01250505;AKOS004118019;4-(4-fluorophenyl)-2-methyl-3-butyn-2-ol;CS-0455884;1-fluoro-4-(3-hydroxy-3-methyl-1-butyn-1-yl)-benzene;1-fluoro-4-(3-hydroxy-3-methyl-1-butyn-1-yl)benzene

Suppliers and Price of 4-(4-Fluorophenyl)-2-methylbut-3-yn-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
4-(4-Fluoro-phenyl)-2-methyl-but-3-yn-2-ol
1g
$ 661.00

Crysdot
4-(4-Fluorophenyl)-2-methylbut-3-yn-2-ol 95+%
5g
$ 700.00

Chemenu
4-(4-fluorophenyl)-2-methylbut-3-yn-2-ol 95%
5g
$ 661.00

Apolloscientific
4-(4-Fluorophenyl)-2-methylbut-3-yn-2-ol 95%
1g
$ 410.00

American Custom Chemicals Corporation
3-BUTYN-2-OL, 4-(4-FLUOROPHENYL)-2-METHYL- 95.00%
5MG
$ 498.09

Alichem
4-(4-Fluorophenyl)-2-methylbut-3-yn-2-ol
5g
$ 777.70

Total 5 raw suppliers

Chemical Property of 4-(4-Fluorophenyl)-2-methylbut-3-yn-2-ol

Chemical Property:

PSA：20.23000
LogP:1.94810
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:178.079393132
Heavy Atom Count:13
Complexity:225

Purity/Quality:

98% ^*data from raw suppliers

4-(4-Fluoro-phenyl)-2-methyl-but-3-yn-2-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C#CC1=CC=C(C=C1)F)O

Technology Process of 4-(4-Fluorophenyl)-2-methylbut-3-yn-2-ol

There total 10 articles about 4-(4-Fluorophenyl)-2-methylbut-3-yn-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 115-19-5
2-methyl-but-3-yn-2-ol

: 460-00-4
1-Bromo-4-fluorobenzene

: 81233-93-4
2-methyl-4-(4-fluorophenyl)-3-butyn-2-ol

Guidance literature:: With N-cyclohexyl-cyclohexanamine; palladium diacetate; tri-tert-butylphosphonium tetraphenylborate; In tetrahydrofuran; at 30 ℃; for 17h; Product distribution / selectivity;

Reference yield: 97.0%

: 352-34-1
4-fluoro-1-iodobenzene

: 115-19-5
2-methyl-but-3-yn-2-ol

: 81233-93-4
2-methyl-4-(4-fluorophenyl)-3-butyn-2-ol

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1002/chem.201705968

Reference yield: 92.0%

: 459-45-0
4-fluorobenzenediazonium tetrafluoroborate

: 115-19-5
2-methyl-but-3-yn-2-ol

: 81233-93-4
2-methyl-4-(4-fluorophenyl)-3-butyn-2-ol

Guidance literature:: With [2,2]bipyridinyl; [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold(I); sodium carbonate; In acetonitrile; at 20 ℃; for 12h; Reagent/catalyst; Concentration;
DOI:10.1002/anie.201503546