Diethyl (1-hydroxy-3-phenylpropyl)phosphonate

Base Information

Chemical Name:Diethyl (1-hydroxy-3-phenylpropyl)phosphonate
CAS No.:81364-33-2
Molecular Formula:C13H21O4P
Molecular Weight:272.281
Hs Code.:
DSSTox Substance ID:DTXSID20513248
Nikkaji Number:J991.056E

Synonyms:81364-33-2;Diethyl (1-hydroxy-3-phenylpropyl)phosphonate;DTXSID20513248

Suppliers and Price of Diethyl (1-hydroxy-3-phenylpropyl)phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Diethyl (1-hydroxy-3-phenylpropyl)phosphonate

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:272.11774614
Heavy Atom Count:18
Complexity:254

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(C(CCC1=CC=CC=C1)O)OCC

Technology Process of Diethyl (1-hydroxy-3-phenylpropyl)phosphonate

There total 7 articles about Diethyl (1-hydroxy-3-phenylpropyl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 104-53-0
3-phenyl-propionaldehyde

: 762-04-9
phosphonic acid diethyl ester

: 81364-33-2
diethyl (1-hydroxy-3-phenylpropyl)phosphonate

Guidance literature:: With hydrotalcite MG₇₀; In neat (no solvent); at 70 ℃; for 2h; Reagent/catalyst;
DOI:10.1002/ejoc.201501434

Reference yield: 95.0%

: 104-53-0
3-phenyl-propionaldehyde

: 122-52-1
triethyl phosphite

: 81364-33-2
diethyl (1-hydroxy-3-phenylpropyl)phosphonate

Guidance literature:: With chloro-trimethyl-silane; lithium perchlorate; In diethyl ether; at 20 ℃; for 0.0833333h;
DOI:10.1080/10426500307904

Reference yield: 93.0%

: 104-53-0
3-phenyl-propionaldehyde

Diethyl phosphonate: 762-04-9,123-22-8
Diethyl phosphonate

: 81364-33-2
diethyl (1-hydroxy-3-phenylpropyl)phosphonate

Guidance literature:: With 1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene; In dichloromethane; at 20 ℃; for 48h; Inert atmosphere; Schlenk technique;
DOI:10.1002/cjoc.201300615