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Technology Process of Avermectin

Avermectin

Base Information
  • Chemical Name:Avermectin
  • CAS No.:73989-17-0
  • Molecular Formula:C44H66O14
  • Molecular Weight:818.99
  • Hs Code.:
  • Mol file:73989-17-0.mol
Avermectin

Synonyms:Aifuding;3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-Tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadeci ne-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-L-arabino-hexopyranoside;(2aZ,4Z,5'S,7S,8Z,20R,20bS)-20,20b-Dihydroxy-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadeci ne-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-L-arabino-hexopyranoside;LS-22263;

Suppliers and Price of Avermectin
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
Total 51 raw suppliers
Chemical Property of Avermectin
Chemical Property:
  • Boiling Point:923.5 °C at 760 mmHg 
  • Flash Point:269.8 °C 
  • PSA：170.06000 
  • Density:1.27 g/cm3 
  • LogP:4.18670 
Purity/Quality:

99% *data from raw suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
Refernces

Nucleophilic addition Reactions of Hindered Unsaturated Boranes. A New Synthesis of Organoboranes

10.1021/ja00237a067

The research primarily focuses on three distinct areas of chemical investigation. The first part examines the electronic states and geometries of a molecule called TME through computational methods such as UHF calculations and CI calculations. The study finds that the singlet state of TME is predicted to be the ground state, conflicting with experimental findings of a triplet ground state. Chemicals like TME and various reagents used in the computational modeling play a role in this research. The second part explores nucleophilic addition reactions of hindered unsaturated boranes, specifically focusing on the activation of olefins by boron-containing groups. Chemicals like vinyldimesitylborane, t-BuLi, Bu4NF, and other organolithium reagents are crucial in this study, enabling the formation of new organoboranes. The third part investigates the chemistry of avermectins, focusing on issues of conjugation, deconjugation, and epimerization. Chemicals such as avermectin derivatives (e.g., 1Aa, 1Bb, 2Bb, 3Bc), LDA, and acetic acid are key in exploring the stability and transformations of these complex molecules.

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