4,5-Bis(4-methoxyphenyl)-2-[(thiophen-2-yl)sulfanyl]-1H-imidazole

Base Information

Chemical Name:4,5-Bis(4-methoxyphenyl)-2-[(thiophen-2-yl)sulfanyl]-1H-imidazole
CAS No.:81527-04-0
Molecular Formula:C21H18N2O2S2
Molecular Weight:394.518
Hs Code.:
DSSTox Substance ID:DTXSID50511015
Wikidata:Q82369612

Synonyms:81527-04-0;SCHEMBL6484619;DTXSID50511015;PMSRSEWSFQOTNC-UHFFFAOYSA-N;4,5-Bis(4-methoxyphenyl)-2-[(thiophen-2-yl)sulfanyl]-1H-imidazole;4,5-bis(4-methoxyphenyl)-2-(2-thienylthio)imidazole

Suppliers and Price of 4,5-Bis(4-methoxyphenyl)-2-[(thiophen-2-yl)sulfanyl]-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4,5-Bis(4-methoxyphenyl)-2-[(thiophen-2-yl)sulfanyl]-1H-imidazole

Chemical Property:

XLogP3:5.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:394.08097017
Heavy Atom Count:27
Complexity:454

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(N=C(N2)SC3=CC=CS3)C4=CC=C(C=C4)OC

Technology Process of 4,5-Bis(4-methoxyphenyl)-2-[(thiophen-2-yl)sulfanyl]-1H-imidazole

There total 3 articles about 4,5-Bis(4-methoxyphenyl)-2-[(thiophen-2-yl)sulfanyl]-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 3437-95-4,149762-92-5
2-Iodothiophene

: 39908-69-5
4,5-bis(4-methoxyphenyl)-2-mercapto-1H-imidazole

: 81527-04-0
4,5-Bis(4-methoxyphenyl)-2-(2-thienylothio)-imidazol

Guidance literature:: With copper; sodium hydride; In N,N-dimethyl-formamide; 1.) 30 min, 2.) 12 h, 100 deg C;
DOI:10.1002/ardp.19833161108

Reference yield:

: 119-52-8
4,4'-dimethoxybenzoin

: 81527-04-0
4,5-Bis(4-methoxyphenyl)-2-(2-thienylothio)-imidazol

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / dimethylformamide / 2 h / Heating

2: 77 percent / 1.) NaH, Cu / dimethylformamide / 1.) 30 min, 2.) 12 h, 100 deg C

With copper; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1002/ardp.19833161108