5,6,7,8-Tetrahydroquinazolin-2-ol

Base Information

Chemical Name:5,6,7,8-Tetrahydroquinazolin-2-ol
CAS No.:81532-77-6
Molecular Formula:C₈H₁₀N₂O
Molecular Weight:150.18
Hs Code.:
European Community (EC) Number:833-345-8
DSSTox Substance ID:DTXSID101281911
Mol file:81532-77-6.mol

Synonyms:81532-77-6;5,6,7,8-Tetrahydroquinazolin-2-ol;5,6,7,8-TETRAHYDRO-1H-QUINAZOLIN-2-ONE;5,6,7,8-tetrahydroquinazolin-2(1{H})-one;SCHEMBL1345477;DBXATJCVRRXUTC-UHFFFAOYSA-N;DTXSID101281911;AKOS030211364;2-hydroxy-5,6,7,8-tetrahydroquinazoline;1,2,5,6,7,8-hexahydroquinazolin-2-one;5,6,7,8-Tetrahydro-2(1H)-quinazolinone;EN300-137745;Z2756994476

Suppliers and Price of 5,6,7,8-Tetrahydroquinazolin-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
5,6,7,8-Tetrahydro-1H-quinazolin-2-one
10g
$ 4075.00

Total 3 raw suppliers

Chemical Property of 5,6,7,8-Tetrahydroquinazolin-2-ol

Chemical Property:

PSA：46.01000
LogP:1.06100
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:150.079312947
Heavy Atom Count:11
Complexity:253

Purity/Quality:: 5,6,7,8-Tetrahydro-1H-quinazolin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2=C(C1)C=NC(=O)N2

Technology Process of 5,6,7,8-Tetrahydroquinazolin-2-ol

There total 1 articles about 5,6,7,8-Tetrahydroquinazolin-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 81532-77-6
5,6,7,8-tetrahydro-2-(1H)-quinazolinone

Guidance literature:: 2-Ureidomethylen-cyclohexanon, NaOH, W.;
DOI:10.1039/j39710001812

Reference yield: 82.0%

: 81532-77-6
5,6,7,8-tetrahydro-2-(1H)-quinazolinone

: 81532-76-5
2-chloro-5,6,7,8-tetrahydroquinazoline

Guidance literature:: With trichlorophosphate; for 4h; Heating;
DOI:10.1248/cpb.31.2254

Reference yield:

: 81532-77-6
5,6,7,8-tetrahydro-2-(1H)-quinazolinone

: 83939-36-0
2-(4-Benzyl-piperazin-1-yl)-5,6,7,8-tetrahydro-quinazoline; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / POCl₃ / 4 h / Heating

2: 68 percent / 3-methyl-butan-1-ol / 7 h / Heating

With trichlorophosphate; In i-Amyl alcohol;
DOI:10.1248/cpb.31.2254