(-)-1,2-Epoxydecane

Base Information

• Chemical Name: (-)-1,2-Epoxydecane
• CAS No.: 81623-66-7
• Molecular Formula: C10H20O
• UNII: 72X24OXG6J
• Nikkaji Number: J941.218B
• Wikidata: Q27266104
• Mol file: 81623-66-7.mol

Synonyms:(-)-1,2-Epoxydecane;Oxirane, 2-octyl-, (2S)-;(S)-2-Octyloxirane;81623-66-7;(S)-1,2-Epoxydecane;Oxirane, octyl-, (S)-;Oxirane, octyl-, (2S)-;1,2-Epoxydecane, (-)-;UNII-72X24OXG6J;72X24OXG6J;2beta-Octyloxirane;1,2(S)-epoxydecane;SCHEMBL3019229;AT36206;Q27266104

Chemical Property of (-)-1,2-Epoxydecane

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 7
• Exact Mass: 156.151415257
• Heavy Atom Count: 11
• Complexity: 90.9

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCC1CO1
• Isomeric SMILES: CCCCCCCC[C@H]1CO1

Technology Process of (-)-1,2-Epoxydecane

There total 6 articles about (-)-1,2-Epoxydecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

(R)-2-bromodecanol (104898-05-7) → (+)-1,2-epoxy-decane (81623-66-7) + (R)-(+)-1,2-epoxydecane (67210-36-0)

Guidance literature:

With sodium methylate; In methanol; Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature; e.e. 96percent;

Reference yield: 45.0%

1,2-Epoxydecane (2404-44-6) → (+)-1,2-epoxy-decane (81623-66-7) + (R)-decane-1,2-diol (87827-60-9)

Guidance literature:

With water; In neat (no solvent); at 0 - 20 ℃; for 8h; enantioselective reaction; Resolution of racemate;

DOI:10.1039/c4cy00594e

Reference yield:

1-Decene (872-05-9,17438-89-0,25189-70-2) → (+)-1,2-epoxy-decane (81623-66-7) + (R)-(+)-1,2-epoxydecane (67210-36-0)

Guidance literature:

With Oxone; C₆H₁₀O₆(C₃H₄)2; tetra(n-butyl)ammonium hydrogensulfate; edetate disodium; sodium hydrogencarbonate; In water; acetonitrile; at -10 ℃; for 1.5h; Product distribution; other reaction time, solvent, reagent;

DOI:10.1021/ja972272g

upstream raw materials:

1,2-decanediol

(R)-2-bromodecanol

1-p-Tolylsulfanyl-decan-2-ol

2-Hydroxycaprinsaeure-methylester

Downstream raw materials:

5(S)-octyl-2(3H)-dihydrofuranone