1-ETHYL-1,2,3,4-TETRAZOLE

Base Information

• Chemical Name: 1-ETHYL-1,2,3,4-TETRAZOLE
• CAS No.: 16687-59-5
• Molecular Formula: C3H6 N4
• Molecular Weight: 98.1074
• Hs Code.: 2933990090
• Mol file: 16687-59-5.mol

Synonyms:1H-Tetrazole,5-ethyl- (8CI,9CI); 5-Ethyl-1H-tetrazole; 5-Ethyl-2H-tetrazole;5-Ethyltetrazole; NSC 11137

Chemical Property of 1-ETHYL-1,2,3,4-TETRAZOLE

Chemical Property:

• Vapor Pressure: 0.0587mmHg at 25°C
• Melting Point: 98-99 °C
• Boiling Point: 232.5°Cat760mmHg
• PKA: 5.07±0.10(Predicted)
• Flash Point: 110.2°C
• PSA: 54.46000
• Density: 1.222g/cm³
• LogP: -0.23790

Purity/Quality:

99%, ^*data from raw suppliers

5-ethyl-1H-tetrazole 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-ETHYL-1,2,3,4-TETRAZOLE

There total 5 articles about 1-ETHYL-1,2,3,4-TETRAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

propiononitrile (107-12-0) → 5-ethyl-1H-1,2,3,4-tetrazole (16687-59-5)

Guidance literature:

With sodium azide; triethylamine hydrochloride; In N,N-dimethyl-formamide; at 130 ℃; for 4h; Microwave irradiation; Inert atmosphere;

DOI:10.1055/s-0032-1318476

Reference yield: 60.0%

propionaldehyde (123-38-6) → 5-ethyl-2H-1,2,3,4-tetrazole (16687-59-5)

Guidance literature:

With sodium azide; hydroxylamine hydrochloride; In N,N-dimethyl-formamide; at 140 ℃; for 8h;

DOI:10.1016/j.ica.2020.120089

Reference yield:

5-vinyltetrazole (18755-47-0) → 5-ethyl-2H-1,2,3,4-tetrazole (16687-59-5)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; for 1h;

upstream raw materials:

propiononitrile

5-vinyltetrazole

propionaldehyde

Downstream raw materials:

N-[1-(5-Ethyl-tetrazol-2-yl)-prop-(Z)-ylidene]-N'-(4-nitro-phenyl)-hydrazine

N-[1-(5-Ethyl-tetrazol-1-yl)-prop-(Z)-ylidene]-N'-(4-nitro-phenyl)-hydrazine

5-ethyl-1-methyl-1H-tetrazole

5-ethyl-2-methyl-2H-tetrazole