Methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate

Base Information

Chemical Name:Methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate
CAS No.:820244-29-9
Molecular Formula:C14H19NO3
Molecular Weight:249.31
Hs Code.:
DSSTox Substance ID:DTXSID70514528

Synonyms:820244-29-9;Methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate;DTXSID70514528

Suppliers and Price of Methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:249.13649347
Heavy Atom Count:18
Complexity:285

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CCC(=O)OC)C(=O)N(C)C1=CC=CC=C1

Technology Process of Methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate

There total 4 articles about Methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 820244-27-7
4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoic acid

: 820244-29-9
methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate

Guidance literature:: In tetrahydrofuran; diethyl ether; at 0 - 20 ℃;
DOI:10.1002/hlca.200490226

Reference yield:

: 73746-79-9,80698-15-3,107242-87-5,10603-03-9,823-22-3
α-methyl-δ-valerolactone

: 820244-29-9
methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / AlCl₃ / 1,2-dichloro-ethane / 5 h / 15 - 25 °C

2: 73 percent / NaIO₄; RuCl₃*H₂O / acetonitrile; ethyl acetate; H₂O / 4 h / 20 °C

3: 100 percent / tetrahydrofuran; diethyl ether / 0 - 20 °C

With ruthenium trichloride; sodium periodate; aluminium trichloride; In tetrahydrofuran; diethyl ether; water; ethyl acetate; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1002/hlca.200490226

Reference yield:

: 542-28-9,26354-94-9
3,4,5,6-tetrahydro-2H-pyran-2-one

: 820244-29-9
methyl 4-methyl-5-[methyl(phenyl)amino]-5-oxopentanoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: LDA / tetrahydrofuran / 1 h / -65 - -60 °C

1.2: 44 percent / 1,3-dimethylimidazolidin-2-one / tetrahydrofuran / 4 h / -65 °C

2.1: 88 percent / AlCl₃ / 1,2-dichloro-ethane / 5 h / 15 - 25 °C

3.1: 73 percent / NaIO₄; RuCl₃*H₂O / acetonitrile; ethyl acetate; H₂O / 4 h / 20 °C

4.1: 100 percent / tetrahydrofuran; diethyl ether / 0 - 20 °C

With ruthenium trichloride; sodium periodate; aluminium trichloride; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; water; ethyl acetate; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1002/hlca.200490226