(5E)-5-(1H-indol-3-ylmethylidene)-2-methyl-3-[5-[2-[(3-nitrophenyl)ami no]acetyl]sulfanyl-1,3,4-thiadiazol-2-yl]imidazol-4-one

Base Information

Chemical Name:(5E)-5-(1H-indol-3-ylmethylidene)-2-methyl-3-[5-[2-[(3-nitrophenyl)ami no]acetyl]sulfanyl-1,3,4-thiadiazol-2-yl]imidazol-4-one
CAS No.:127227-41-2
Molecular Formula:C₂₃H₁₇N₇O₄S₂
Molecular Weight:519.564
Hs Code.:
Mol file:127227-41-2.mol

Synonyms:Ethanethioicacid, [(3-nitrophenyl)amino]-,S-[5-[4,5-dihydro-4-(1H-indol-3-ylmethylene)-2-methyl-5-oxo-1H-imidazol-1-yl]-1,3,4-thiadiazol-2-yl]ester (9CI)

Suppliers and Price of (5E)-5-(1H-indol-3-ylmethylidene)-2-methyl-3-[5-[2-[(3-nitrophenyl)ami no]acetyl]sulfanyl-1,3,4-thiadiazol-2-yl]imidazol-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (5E)-5-(1H-indol-3-ylmethylidene)-2-methyl-3-[5-[2-[(3-nitrophenyl)ami no]acetyl]sulfanyl-1,3,4-thiadiazol-2-yl]imidazol-4-one

Chemical Property:

Vapor Pressure:6.28E-26mmHg at 25°C
Boiling Point:804.7°Cat760mmHg
Flash Point:440.5°C
PSA：202.70000
Density:1.61g/cm³
LogP:4.56130

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (5E)-5-(1H-indol-3-ylmethylidene)-2-methyl-3-[5-[2-[(3-nitrophenyl)ami no]acetyl]sulfanyl-1,3,4-thiadiazol-2-yl]imidazol-4-one

There total 3 articles about (5E)-5-(1H-indol-3-ylmethylidene)-2-methyl-3-[5-[2-[(3-nitrophenyl)ami no]acetyl]sulfanyl-1,3,4-thiadiazol-2-yl]imidazol-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 127227-47-8
(3-Nitro-phenylamino)-acetyl chloride

: 127227-36-5
3-<4'-(1''H-indol-3''-ylmethylene)-2'-methyl-5'-(4'H)-oxo-1'H-imidazol-1'-yl>-5-mercapto-1,3,4-thiadiazole

: 127227-41-2
(3-Nitro-phenylamino)-thioacetic acid S-(5-{4-[1-(1H-indol-3-yl)-meth-(Z)-ylidene]-2-methyl-5-oxo-4,5-dihydro-imidazol-1-yl}-[1,3,4]thiadiazol-2-yl) ester

Guidance literature:: With potassium carbonate; In acetone; for 4h; Heating;

Reference yield:

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 127227-41-2
(3-Nitro-phenylamino)-thioacetic acid S-(5-{4-[1-(1H-indol-3-yl)-meth-(Z)-ylidene]-2-methyl-5-oxo-4,5-dihydro-imidazol-1-yl}-[1,3,4]thiadiazol-2-yl) ester

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / sodium acetate, acetic anhydride / 2 h / Heating

2: 70 percent / 0.33 h / 140 °C / Heating

3: 70 percent / K₂CO₃ / acetone / 4 h / Heating

With sodium acetate; acetic anhydride; potassium carbonate; In acetone;

Reference yield:

: 54753-57-0,70082-68-7,70082-69-8
4-(1'H-indol-3'-ylmethylene)-2-methyl-5(4H)oxazolone

: 127227-41-2
(3-Nitro-phenylamino)-thioacetic acid S-(5-{4-[1-(1H-indol-3-yl)-meth-(Z)-ylidene]-2-methyl-5-oxo-4,5-dihydro-imidazol-1-yl}-[1,3,4]thiadiazol-2-yl) ester

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / 0.33 h / 140 °C / Heating

2: 70 percent / K₂CO₃ / acetone / 4 h / Heating

With potassium carbonate; In acetone;