Technology Process of 3-Cyclohexene-1-carboxylic acid, 6-(azidocarbonyl)-, 1,1-dimethylethyl
ester, (1R,6S)-
There total 5 articles about 3-Cyclohexene-1-carboxylic acid, 6-(azidocarbonyl)-, 1,1-dimethylethyl
ester, (1R,6S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 98 percent / pig liver esterase / H2O; acetone / 30 °C
2: H2SO4 / CH2Cl2 / 144 h / Ambient temperature
3: 82 percent / NaOH / H2O; methanol / 18 h / Ambient temperature
4: 1) ClCO2C2H5, 2) NaN3 / acetone / 1) -25 deg C, 2) -10 deg C then 1 h room temp.
With
sodium hydroxide; sodium azide; pig liver esterase; chloroformic acid ethyl ester;
sulfuric acid;
In
methanol; dichloromethane; water; acetone;
DOI:10.1016/S0040-4039(01)81230-2
- Guidance literature:
-
Multi-step reaction with 3 steps
1: H2SO4 / CH2Cl2 / 144 h / Ambient temperature
2: 82 percent / NaOH / H2O; methanol / 18 h / Ambient temperature
3: 1) ClCO2C2H5, 2) NaN3 / acetone / 1) -25 deg C, 2) -10 deg C then 1 h room temp.
With
sodium hydroxide; sodium azide; chloroformic acid ethyl ester;
sulfuric acid;
In
methanol; dichloromethane; water; acetone;
DOI:10.1016/S0040-4039(01)81230-2
- Guidance literature:
-
With
sodium azide; chloroformic acid ethyl ester;
Multistep reaction;
1.) Et3N, acetone, -25 deg C 2.) 1h r. t.;
DOI:10.1248/cpb.38.350
