Technology Process of 1H-Pyrazole-3-carboxylic acid,
5-[4-[(4-chlorophenyl)methoxy]-2-(phenylmethoxy)phenyl]-1-methyl-
There total 7 articles about 1H-Pyrazole-3-carboxylic acid,
5-[4-[(4-chlorophenyl)methoxy]-2-(phenylmethoxy)phenyl]-1-methyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: potassium carbonate; potassium iodide; tetrabutylammomium bromide / acetone / Reflux
2: potassium carbonate / N,N-dimethyl-formamide / 5 h / 50 °C
3: sodium ethanolate / ethanol; tetrahydrofuran / 8 h / Reflux
4: hydrazine hydrate; acetic acid / 8 h / Reflux
5: potassium carbonate / acetone / 2 h / Reflux
6: sodium hydroxide; methanol / tetrahydrofuran / 0.5 h / Reflux
With
methanol; tetrabutylammomium bromide; sodium ethanolate; potassium carbonate; hydrazine hydrate; acetic acid; potassium iodide; sodium hydroxide;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.2174/1573406411309080013
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 50 °C
2: sodium ethanolate / ethanol; tetrahydrofuran / 8 h / Reflux
3: hydrazine hydrate; acetic acid / 8 h / Reflux
4: potassium carbonate / acetone / 2 h / Reflux
5: sodium hydroxide; methanol / tetrahydrofuran / 0.5 h / Reflux
With
methanol; sodium ethanolate; potassium carbonate; hydrazine hydrate; acetic acid; sodium hydroxide;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.2174/1573406411309080013
