Silane, 1,1'-(1-propyne-1,3-diyl)bis[1,1,1-tris(1-methylethyl)-

Base Information

Chemical Name:Silane, 1,1'-(1-propyne-1,3-diyl)bis[1,1,1-tris(1-methylethyl)-
CAS No.:82192-59-4
Molecular Formula:C21H44Si2
Molecular Weight:352.751
Hs Code.:
Mol file:82192-59-4.mol

Synonyms:1,3-bistriisopropylsilanylpropyne;1,3-bis-TIPS-propyne;1,3-BIS(TRIISOPROPYLSILYL)PROPYNE;prop-1-yne-1,3-diylbis(tripropan-2-ylsilane);

Suppliers and Price of Silane, 1,1'-(1-propyne-1,3-diyl)bis[1,1,1-tris(1-methylethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Silane, 1,1'-(1-propyne-1,3-diyl)bis[1,1,1-tris(1-methylethyl)-

Chemical Property:

PSA：0.00000
LogP:7.88660
Solubility.:both the reagent and its lithio derivative are soluble in ether or THF.

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Physical properties bp 130–135°C/0.08 mmHg; d 0.846 g cm?3.
Uses 1,3-Bis(triisopropylsilyl)propyne is a precursor of a stereoselective bulky C3 nucleophile, functionalized Peterson reagent.The main use of the title reagent is as a precursor of the lithium derivative. 1,3-Bis(triisopropylsilyl)propyne is cleanly lithiated by treatment with equiv of n-butyllithium in THF at ?20°C (15 min) to what is probably an equilibrium mixture of propargylic and allenic species (1) and (2) (eq 1).The bulky triisopropylsilyl (TIPS) group serves as a controlling group in the addition of (1/2) to electrophiles.

Technology Process of Silane, 1,1'-(1-propyne-1,3-diyl)bis[1,1,1-tris(1-methylethyl)-

There total 1 articles about Silane, 1,1'-(1-propyne-1,3-diyl)bis[1,1,1-tris(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 80522-42-5
triisopropylsilyl trifluoromethanesulfonate

: 82192-59-4
1,3-bis(triisopropylsilyl)prop-1-yne

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / diethyl ether / -40 - 0 °C

2: n-butyllithium-tetramethylene diamine / diethyl ether / 2 h / -15 °C

3: 100 percent / 1 h / -78 - -40 °C

With n-butyllithium; 1,4-diaminobutane; In diethyl ether;
DOI:10.1016/S0040-4039(00)86930-0

Reference yield: 69.0%

: 82192-59-4
1,3-bis(triisopropylsilyl)prop-1-yne

: 344315-39-5
C₄₄H₆₀O₈S₂Si

: 344315-40-8
C₅₆H₈₂O₇S₂Si₂

Guidance literature:: With n-butyllithium;
DOI:10.1016/S0040-4039(01)00286-6

Reference yield: 55.0%

: 82192-59-4
1,3-bis(triisopropylsilyl)prop-1-yne

: 75648-76-9
{(1S,3aS,5aS,6S,9aR)-1-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-dodecahydro-pyrrolo[1,2-a]quinolin-6-yl}-acetaldehyde

: 86197-22-0
1α,2,3,3aα,4,5,5aβ,6α,7,8,9,9aβ-dodecahydro-1-<2-<(tert-butyldiphenylsilyl)oxy>ethyl>-6-<5-(triiisopropylsilyl)-2(Z)-penten-4-ynyl>pyrrolo<1,2-a>quinoline

: 86258-59-5
1α,2,3,3aα,4,5,5aβ,6α,7,8,9,9aβ-dodecahydro-1-<2-<(tert-butyldiphenylsilyl)oxy>ethyl>-6-<5-(triiisopropylsilyl)-2(E)-penten-4-ynyl>pyrrolo<1,2-a>quinoline

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; 1.) -20 deg C, 15 min, 2.) -78 deg C -> RT, 12 h;
DOI:10.1021/ja00354a031