2-Bromo-5-(trifluoromethyl)isonicotinic acid

Base Information

• Chemical Name: 2-Bromo-5-(trifluoromethyl)isonicotinic acid
• CAS No.: 823222-03-3
• Molecular Formula: C₇H₃BrF₃NO₂
• Molecular Weight: 270.006
• Hs Code.: 2933399990
• Mol file: 823222-03-3.mol

Synonyms:4-Pyridinecarboxylic acid,2-bromo-5-(trifluoromethyl);

Chemical Property of 2-Bromo-5-(trifluoromethyl)isonicotinic acid

Chemical Property:

• PSA: 50.19000
• LogP: 2.56110
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-5-(trifluoromethyl)isonicotinic acid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Bromo-5-(trifluoromethyl)isonicotinic acid

There total 1 articles about 2-Bromo-5-(trifluoromethyl)isonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-chloro-5-(trifluoromethyl)pyridine-4-carboxylic acid (505084-58-2) → 2-bromo-5-(trifluoromethyl)pyridine-4-carboxylic acid (823222-03-3)

Guidance literature:

With trimethylsilyl bromide;

DOI:10.1016/j.tet.2004.09.106

upstream raw materials:

2-chloro-5-(trifluoromethyl)pyridine-4-carboxylic acid

Refernces