Benzamide, 2-[[(acetyloxy)acetyl]amino]-N-2-propynyl-

Base Information

Chemical Name:Benzamide, 2-[[(acetyloxy)acetyl]amino]-N-2-propynyl-
CAS No.:823235-08-1
Molecular Formula:C14H14N2O4
Molecular Weight:274.276
Hs Code.:
DSSTox Substance ID:DTXSID10460277
Wikidata:Q82284275

Synonyms:823235-08-1;Benzamide, 2-[[(acetyloxy)acetyl]amino]-N-2-propynyl-;DTXSID10460277

Suppliers and Price of Benzamide, 2-[[(acetyloxy)acetyl]amino]-N-2-propynyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzamide, 2-[[(acetyloxy)acetyl]amino]-N-2-propynyl-

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:274.09535693
Heavy Atom Count:20
Complexity:424

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OCC(=O)NC1=CC=CC=C1C(=O)NCC#C

Technology Process of Benzamide, 2-[[(acetyloxy)acetyl]amino]-N-2-propynyl-

There total 2 articles about Benzamide, 2-[[(acetyloxy)acetyl]amino]-N-2-propynyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 4943-83-3
2-amino-N-(prop-2-yn-1-yl)benzamide

: 13831-31-7
Acetoxyacetyl chloride

: 823235-08-1
acetic acid (2-prop-2-ynylcarbamoylphenylcarbamoyl)methyl ester

Guidance literature:: With triethylamine; In benzene; at 20 - 40 ℃;
DOI:10.1021/ol0479848

Reference yield:

: 118-48-9
isatoic anhydride

: 823235-08-1
acetic acid (2-prop-2-ynylcarbamoylphenylcarbamoyl)methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / dimethylformamide / 3 h / 40 - 50 °C

2: 68 percent / Et₃N / benzene / 20 - 40 °C

With triethylamine; In N,N-dimethyl-formamide; benzene;
DOI:10.1021/ol0479848