6-(2,2-Diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl(1,2,4)triazolo(1,5-b)pyridazine

Base Information

Chemical Name:6-(2,2-Diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl(1,2,4)triazolo(1,5-b)pyridazine
CAS No.:152537-76-3
Molecular Formula:C₁₄H₂₃N₅O₃S
Molecular Weight:341.434
Hs Code.:
DSSTox Substance ID:DTXSID00165062
Wikidata:Q83034210
Mol file:152537-76-3.mol

Synonyms:1-Butanesulfonamide, 2-(((2,8-dimethyl(1,2,4)triazolo(1,5-b)pyridazin-6-yl)oxy)methyl)-2-ethyl-;6-(2,2-Diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl(1,2,4)triazolo(1,5-b)pyridazine;152537-76-3;6-(2,2-diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl[1,2,4]triazolo[1,5-b]pyridazine;SCHEMBL8310851;DTXSID00165062;PGMZSVUUNSGEQP-UHFFFAOYSA-N;LS-45972

Suppliers and Price of 6-(2,2-Diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl(1,2,4)triazolo(1,5-b)pyridazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 0 raw suppliers

Chemical Property of 6-(2,2-Diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl(1,2,4)triazolo(1,5-b)pyridazine

Chemical Property:

Boiling Point:°Cat760mmHg
PKA:10.46±0.60(Predicted)
Flash Point:°C
PSA：120.85000
Density:1.35g/cm³
LogP:2.99590
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:341.15216079
Heavy Atom Count:23
Complexity:491

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(CC)(COC1=NN2C(=NC(=N2)C)C(=C1)C)CS(=O)(=O)N

Technology Process of 6-(2,2-Diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl(1,2,4)triazolo(1,5-b)pyridazine

There total 4 articles about 6-(2,2-Diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl(1,2,4)triazolo(1,5-b)pyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-(N,N-dimethylamino-methylene)aminosulfonyl-2,2-diethyl-1-propanol

: 175215-30-2
6-chloro-2,8-dimethyl[1,2,4]triazolo[1,5-b]pyridazine

: 152537-76-3
6-(2,2-diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl[1,2,4]triazolo[1,5-b]pyridazine

Guidance literature:

Reference yield:

: 64068-00-4
3-amino-6-chloro-4-methylpyridazine

: 152537-76-3
6-(2,2-diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl[1,2,4]triazolo[1,5-b]pyridazine

Guidance literature:: Multi-step reaction with 3 steps

1: toluene

2: 1.) NH₂OH*HCl, 2.) polyphosphoric acid

3: 1.) NaH / 1.) DMF, RT, 1 h, 2.) DMF, RT, 18 h

With PPA; hydroxylamine hydrochloride; sodium hydride; In toluene;
DOI:10.1248/cpb.45.1447

Reference yield:

: 68675-28-5
N'-(6-chloro-4-methyl-pyridazin-3-yl)-N,N-dimethyl-acetamidine

: 152537-76-3
6-(2,2-diethyl-3-sulfamoyl-1-propoxy)-2,8-dimethyl[1,2,4]triazolo[1,5-b]pyridazine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NH₂OH*HCl, 2.) polyphosphoric acid

2: 1.) NaH / 1.) DMF, RT, 1 h, 2.) DMF, RT, 18 h

With PPA; hydroxylamine hydrochloride; sodium hydride;
DOI:10.1248/cpb.45.1447