Technology Process of 9H-Purine-9-carboxylic acid, 2-nitroso-6-(phenylmethoxy)-,
1,1-dimethylethyl ester
There total 8 articles about 9H-Purine-9-carboxylic acid, 2-nitroso-6-(phenylmethoxy)-,
1,1-dimethylethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 82 percent / DMAP / CH2Cl2 / 16 h / 20 °C
2: 90 percent / TFAA; tetrabutylammonium nitrate / CH2Cl2 / 1 h / 0 °C
3: H2; acetic acid / Pd/C / methanol; ethyl acetate / 0.5 h / 760 Torr
4: aq. NaIO4 / methanol; ethyl acetate; CH2Cl2 / 0 °C
With
dmap; sodium periodate; hydrogen; tetrabutylammonium nitrate; acetic acid; trifluoroacetic anhydride;
palladium on activated charcoal;
In
methanol; dichloromethane; ethyl acetate;
DOI:10.1021/jm049556d
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 90 percent / TFAA; tetrabutylammonium nitrate / CH2Cl2 / 1 h / 0 °C
2: H2; acetic acid / Pd/C / methanol; ethyl acetate / 0.5 h / 760 Torr
3: aq. NaIO4 / methanol; ethyl acetate; CH2Cl2 / 0 °C
With
sodium periodate; hydrogen; tetrabutylammonium nitrate; acetic acid; trifluoroacetic anhydride;
palladium on activated charcoal;
In
methanol; dichloromethane; ethyl acetate;
DOI:10.1021/jm049556d
- Guidance literature:
-
Multi-step reaction with 2 steps
1: H2; acetic acid / Pd/C / methanol; ethyl acetate / 0.5 h / 760 Torr
2: aq. NaIO4 / methanol; ethyl acetate; CH2Cl2 / 0 °C
With
sodium periodate; hydrogen; acetic acid;
palladium on activated charcoal;
In
methanol; dichloromethane; ethyl acetate;
DOI:10.1021/jm049556d
