4-Quinolinol, 2-phenyl-7-(trifluoromethoxy)-

Base Information

Chemical Name:4-Quinolinol, 2-phenyl-7-(trifluoromethoxy)-
CAS No.:825620-21-1
Molecular Formula:C₁₆H₁₀F₃NO₂
Molecular Weight:305.256
Hs Code.:
DSSTox Substance ID:DTXSID70465223

Synonyms:825620-21-1;2-PHENYL-7-(TRIFLUOROMETHOXY)QUINOLIN-4-OL;4-Quinolinol, 2-phenyl-7-(trifluoromethoxy)-;DTXSID70465223

Suppliers and Price of 4-Quinolinol, 2-phenyl-7-(trifluoromethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Quinolinol, 2-phenyl-7-(trifluoromethoxy)-

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:305.06636305
Heavy Atom Count:22
Complexity:455

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=O)C3=C(N2)C=C(C=C3)OC(F)(F)F

Technology Process of 4-Quinolinol, 2-phenyl-7-(trifluoromethoxy)-

There total 3 articles about 4-Quinolinol, 2-phenyl-7-(trifluoromethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-Phenyl-3-[(E)-3-trifluoromethoxy-phenylimino]-propionamide

: 825620-21-1
2-phenyl-7-(trifluoromethoxy)quinolin-4-ol

Guidance literature:: In diphenylether; at 240 ℃; for 1h;
DOI:10.1021/jm0494523

Reference yield:

: 3446-58-0
3-oxo-3-phenylpropanamide

: 825620-21-1
2-phenyl-7-(trifluoromethoxy)quinolin-4-ol

Guidance literature:: Multi-step reaction with 2 steps

1: m-trifluoromethoxyaniline hydrochloride / toluene / Heating

2: diphenyl ether / 1 h / 240 °C

With m-trifluoromethoxyaniline hydrochloride; In diphenylether; toluene;
DOI:10.1021/jm0494523

Reference yield:

: 1535-73-5
m-trifluoromethoxyaniline

: 825620-21-1
2-phenyl-7-(trifluoromethoxy)quinolin-4-ol

Guidance literature:: Multi-step reaction with 2 steps

1: m-trifluoromethoxyaniline hydrochloride / toluene / Heating

2: diphenyl ether / 1 h / 240 °C

With m-trifluoromethoxyaniline hydrochloride; In diphenylether; toluene;
DOI:10.1021/jm0494523