4,5-Dimethoxy-1h-isoindole-1,3(2h)-dione

Base Information

Chemical Name:4,5-Dimethoxy-1h-isoindole-1,3(2h)-dione
CAS No.:4667-74-7
Molecular Formula:C10H9NO4
Molecular Weight:207.186
Hs Code.:
NSC Number:28982
DSSTox Substance ID:DTXSID00282960
Nikkaji Number:J1.736.052C
Wikidata:Q82017367
Mol file:4667-74-7.mol

Synonyms:4,5-dimethoxy-1h-isoindole-1,3(2h)-dione;4667-74-7;4,5-dimethoxyisoindole-1,3-dione;NSC28982;3,4-dimethoxyphthalimide;Oprea1_086600;Oprea1_537226;3,4-Dimethoxy-phthalsaureimid;SCHEMBL6157005;DTXSID00282960;1H-Isoindole-1, 4,5-dimethoxy-;NSC 28982;NSC-28982;AKOS001360812;1H-Isoindole-1,3(2H)-dione, 4,5-dimethoxy-;AE-641/00776015;SR-01000312086;4,5-dimethoxy-2,3-dihydro-1H-isoindole-1,3-dione;SR-01000312086-1

Suppliers and Price of 4,5-Dimethoxy-1h-isoindole-1,3(2h)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4,5-Dimethoxy-1h-isoindole-1,3(2h)-dione

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.331g/cm³
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:207.05315777
Heavy Atom Count:15
Complexity:291

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C2=C(C=C1)C(=O)NC2=O)OC

Technology Process of 4,5-Dimethoxy-1h-isoindole-1,3(2h)-dione

There total 3 articles about 4,5-Dimethoxy-1h-isoindole-1,3(2h)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 25984-84-3
3-[1-[2-(2-Dimethylamino-ethyl)-4,5-dimethoxy-phenyl]-meth-(Z)-ylidene]-6,7-dimethoxy-2,3-dihydro-isoindol-1-one

: 4667-74-7
3,4-dimethoxyphthalimide

: 78388-10-0
2-(2-dimethylaminoethyl)-4,5-dimethoxybenzaldehyde

Guidance literature:: With hydrogenchloride; sodium periodate; osmium(VIII) oxide; In water; for 15h; Ambient temperature; pH= 2-4;
DOI:10.1016/S0040-4020(01)92023-X

Reference yield:

: 79622-66-5
1-Chlor-4,5-dimethoxy-isobenzofuran-3-on

: 5,6-dimethoxyphthalimide

: 4667-74-7
3,4-dimethoxyphthalimide

: potassium 5,6-dimethoxy-2-(N-hydroxyimino)methanoylbenzoate

Guidance literature:: With hydroxylamine hydrochloride; potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 48h;
DOI:10.1007/s10870-012-0377-7

Reference yield:

: 519-05-1
opianic acid

: 5,6-dimethoxyphthalimide

: 4667-74-7
3,4-dimethoxyphthalimide

: potassium 5,6-dimethoxy-2-(N-hydroxyimino)methanoylbenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride

2: hydroxylamine hydrochloride; potassium carbonate / N,N-dimethyl-formamide / 48 h / 25 °C

With thionyl chloride; hydroxylamine hydrochloride; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1007/s10870-012-0377-7