Phosphonic acid, [(2S)-2-amino-2-phenylethyl]-, dimethyl ester

Base Information

Chemical Name:Phosphonic acid, [(2S)-2-amino-2-phenylethyl]-, dimethyl ester
CAS No.:827320-91-2
Molecular Formula:C10H16NO3P
Molecular Weight:229.216
Hs Code.:
DSSTox Substance ID:DTXSID80460527
Nikkaji Number:J2.112.917H
Wikidata:Q82284593

Synonyms:827320-91-2;Phosphonic acid, [(2S)-2-amino-2-phenylethyl]-, dimethyl ester;DTXSID80460527

Suppliers and Price of Phosphonic acid, [(2S)-2-amino-2-phenylethyl]-, dimethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phosphonic acid, [(2S)-2-amino-2-phenylethyl]-, dimethyl ester

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:229.08678037
Heavy Atom Count:15
Complexity:221

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COP(=O)(CC(C1=CC=CC=C1)N)OC
Isomeric SMILES:COP(=O)(C[C@H](C1=CC=CC=C1)N)OC

Technology Process of Phosphonic acid, [(2S)-2-amino-2-phenylethyl]-, dimethyl ester

There total 3 articles about Phosphonic acid, [(2S)-2-amino-2-phenylethyl]-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₈H₂₉NO₃P₂

: 827320-91-2
dimethyl (2S)-β-amino-β-phenylethylphosphonate

Guidance literature:: With water; at 55 ℃; for 4h;
DOI:10.1002/ejoc.200400420

Reference yield:

: 161694-19-5
dimethyl (R)-(2-hydroxy-2-phenylethyl)phosphonate

: 827320-91-2
dimethyl (2S)-β-amino-β-phenylethylphosphonate

Guidance literature:: Multi-step reaction with 3 steps

1: Ph₃P; DEAD; HN₃ / CH₂Cl₂; CHCl₃ / -15 - 20 °C

2: benzene / 2 h / 20 °C

3: H₂O / 4 h / 55 °C

With tris-(2-chloro-ethyl)-amine; water; triphenylphosphine; diethylazodicarboxylate; In dichloromethane; chloroform; benzene; 1: Mitsunobu reaction;
DOI:10.1002/ejoc.200400420

Reference yield:

: ((S)-2-Azido-2-phenyl-ethyl)-phosphonic acid dimethyl ester

: 827320-91-2
dimethyl (2S)-β-amino-β-phenylethylphosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: benzene / 2 h / 20 °C

2: H₂O / 4 h / 55 °C

With water; In benzene;
DOI:10.1002/ejoc.200400420