1-((1,3-Diphenyl-1H-pyrazol-4-yl)carbonyl)-4-(phenylmethyl)piperazine monohydrochloride

Base Information

Chemical Name:1-((1,3-Diphenyl-1H-pyrazol-4-yl)carbonyl)-4-(phenylmethyl)piperazine monohydrochloride
CAS No.:125103-41-5
Molecular Formula:C₂₇H₂₆N₄O*ClH
Molecular Weight:458.991
Hs Code.:
DSSTox Substance ID:DTXSID80925020
Mol file:125103-41-5.mol

Synonyms:1-((1,3-Diphenyl-1H-pyrazol-4-yl)carbonyl)-4-(phenylmethyl)piperazine monohydrochloride;125103-41-5;Piperazine, 1-((1,3-diphenyl-1H-pyrazol-4-yl)carbonyl)-4-(phenylmethyl)-, monohydrochloride;(4-benzylpiperazin-1-yl)-(1,3-diphenylpyrazol-4-yl)methanone;hydrochloride;C27H26N4O.ClH;DTXSID80925020;C27-H26-N4-O.Cl-H;LS-111972;(4-Benzylpiperazin-1-yl)(1,3-diphenyl-1H-pyrazol-4-yl)methanone--hydrogen chloride (1/1)

Suppliers and Price of 1-((1,3-Diphenyl-1H-pyrazol-4-yl)carbonyl)-4-(phenylmethyl)piperazine monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-((1,3-Diphenyl-1H-pyrazol-4-yl)carbonyl)-4-(phenylmethyl)piperazine monohydrochloride

Chemical Property:

Vapor Pressure:2.42E-15mmHg at 25°C
Boiling Point:620.9°Cat760mmHg
Flash Point:329.3°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:458.1873392
Heavy Atom Count:33
Complexity:587

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC2=CC=CC=C2)C(=O)C3=CN(N=C3C4=CC=CC=C4)C5=CC=CC=C5.Cl

Technology Process of 1-((1,3-Diphenyl-1H-pyrazol-4-yl)carbonyl)-4-(phenylmethyl)piperazine monohydrochloride

There total 2 articles about 1-((1,3-Diphenyl-1H-pyrazol-4-yl)carbonyl)-4-(phenylmethyl)piperazine monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.8%

: 2759-28-6
1-phenylmethylpiperazine

: 373627-25-9
1,3-diphenylpyrazole-4-carboxylic acid chloride

: 125103-41-5
(4-Benzyl-piperazin-1-yl)-(1,3-diphenyl-1H-pyrazol-4-yl)-methanone; hydrochloride

Guidance literature:: In 1,2-dichloro-ethane; benzene; Ambient temperature;
DOI:10.1007/BF00766389

Reference yield:

: 77169-12-1
1,3-diphenyl-1H-pyrazole-4-carboxylic acid

: 125103-41-5
(4-Benzyl-piperazin-1-yl)-(1,3-diphenyl-1H-pyrazol-4-yl)-methanone; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 1 h / Heating

2: 70.8 percent / benzene; 1,2-dichloro-ethane / Ambient temperature

With thionyl chloride; In 1,2-dichloro-ethane; benzene;
DOI:10.1007/BF00766389