(5R)-5-(Hydroxymethyl)-3-[4-(methylsulfanyl)phenyl]-1,3-oxazolidin-2-one

Base Information

Chemical Name:(5R)-5-(Hydroxymethyl)-3-[4-(methylsulfanyl)phenyl]-1,3-oxazolidin-2-one
CAS No.:82796-40-5
Molecular Formula:C11H13NO3S
Molecular Weight:239.295
Hs Code.:
DSSTox Substance ID:DTXSID80516013
Nikkaji Number:J356.703F
Wikidata:Q82377214

Synonyms:82796-40-5;SCHEMBL6607528;DTXSID80516013;QPXCTJMLKKNYGA-SECBINFHSA-N;(5R)-5-(Hydroxymethyl)-3-[4-(methylsulfanyl)phenyl]-1,3-oxazolidin-2-one;5(R)-hydroxymethyl-3-(4-methylthiophenyl)oxazolidin-2-one

Suppliers and Price of (5R)-5-(Hydroxymethyl)-3-[4-(methylsulfanyl)phenyl]-1,3-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (5R)-5-(Hydroxymethyl)-3-[4-(methylsulfanyl)phenyl]-1,3-oxazolidin-2-one

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:239.06161445
Heavy Atom Count:16
Complexity:254

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=CC=C(C=C1)N2CC(OC2=O)CO
Isomeric SMILES:CSC1=CC=C(C=C1)N2C[C@@H](OC2=O)CO

Technology Process of (5R)-5-(Hydroxymethyl)-3-[4-(methylsulfanyl)phenyl]-1,3-oxazolidin-2-one

There total 2 articles about (5R)-5-(Hydroxymethyl)-3-[4-(methylsulfanyl)phenyl]-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 121373-23-7
(R)-<3-<4-(methylthio)phenyl>-2-oxo-5-oxazolidinyl>methyl butyrate

: 82796-40-5
5(R)-hydroxymethyl-3-(4-methylthiophenyl)oxazolidin-2-one

Guidance literature:: With sodium methylate; In methanol; for 2h; Ambient temperature;
DOI:10.1021/jm00128a003

Reference yield:

: 1632-84-4
4-(methylthio)phenyl isocyanate

: 82796-40-5
5(R)-hydroxymethyl-3-(4-methylthiophenyl)oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / LiBr, n-Bu₃PO / xylene / 2 h / Heating

2: 100 percent / sodium methoxide / methanol / 2 h / Ambient temperature

With Tributylphosphine oxide; sodium methylate; lithium bromide; In methanol; xylene;
DOI:10.1021/jm00128a003