5-(4-Methylphenyl)-1,2-thiazole

Base Information

Chemical Name:5-(4-Methylphenyl)-1,2-thiazole
CAS No.:49602-75-7
Molecular Formula:C10H9 N S
Molecular Weight:175.2502
Hs Code.:
NSC Number:111909
DSSTox Substance ID:DTXSID10296831
Wikidata:Q82037616
Mol file:49602-75-7.mol

Synonyms:49602-75-7;5-(4-methylphenyl)-1,2-thiazole;Isothiazole,5-(4-methylphenyl)-;5-p-tolylisothiazole;NSC111909;5-(p-tolyl)-isothiazole;SCHEMBL9290080;DTXSID10296831;AKOS006284159;NSC-111909

Suppliers and Price of 5-(4-Methylphenyl)-1,2-thiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-(4-METHYLPHENYL)ISOTHIAZOLE 98.00%
500G
$ 4631.55

American Custom Chemicals Corporation
5-(4-METHYLPHENYL)ISOTHIAZOLE 98.00%
100G
$ 2960.27

Total 5 raw suppliers

Chemical Property of 5-(4-Methylphenyl)-1,2-thiazole

Chemical Property:

Vapor Pressure:0.167mmHg at 25°C
Boiling Point:220.5 °C at 760 mmHg
Flash Point:80.6 °C
PSA：41.13000
Density:1.14 g/cm³
LogP:3.11850
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:175.04557046
Heavy Atom Count:12
Complexity:141

Purity/Quality:

99% ^*data from raw suppliers

5-(4-METHYLPHENYL)ISOTHIAZOLE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=CC=NS2

Technology Process of 5-(4-Methylphenyl)-1,2-thiazole

There total 7 articles about 5-(4-Methylphenyl)-1,2-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 31639-16-4
β-N,N-dimethylaminovinyl tolyl thioketone

: 49602-75-7
5-p-Tolylisothiazole

Guidance literature:: With pyridine; hydroxylamine-O-sulfonic acid; In methanol; ethanol; for 0.5h; Ambient temperature;
DOI:10.1021/jo01312a011

Reference yield: 32.0%

: 4083-64-1
Tosyl isocyanate

: 4-Methyl-dithiobenzoic acid 2-hydroxyimino-ethyl ester

: 49602-75-7
5-p-Tolylisothiazole

Guidance literature:

Reference yield:

: 18103-98-5
3-dimethylamino-1-(4-methyl-phenyl)-2-propen-1-one

: 49602-75-7
5-p-Tolylisothiazole

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Phosphorus oxychloride, 2.) Sodium perchlorate monohydrate / 1.) anhydr. Dichloromethane, room temp., 20 min, 0 deg C, 10 min, 2.) Dichloromethane/water, 0 deg C, 20 min

2: 73 percent / Sodium sulfide nonahydrate / dimethylformamide; H₂O / 2 h / Ambient temperature

3: 65 percent / Pyridine, Hydroxylamine-O-sulfonic acid / ethanol; methanol / 0.5 h / Ambient temperature

With pyridine; sodium sulfide; sodium perchlorate; hydroxylamine-O-sulfonic acid; trichlorophosphate; In methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jo01312a011