4-Benzyl-1-(3-nitro-phenyl)-piperidine

Base Information

Chemical Name:4-Benzyl-1-(3-nitro-phenyl)-piperidine
CAS No.:831203-53-3
Molecular Formula:C18H20N2O2
Molecular Weight:296.369
Hs Code.:
DSSTox Substance ID:DTXSID70470074
Wikidata:Q82298045

Synonyms:4-Benzyl-1-(3-nitro-phenyl)-piperidine;831203-53-3;SCHEMBL6427173;DTXSID70470074;RPFRWDJZSYYHJI-UHFFFAOYSA-N

Suppliers and Price of 4-Benzyl-1-(3-nitro-phenyl)-piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Benzyl-1-(3-nitro-phenyl)-piperidine

Chemical Property:

PSA：49.06000
LogP:4.64210
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:296.152477885
Heavy Atom Count:22
Complexity:355

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-]

Technology Process of 4-Benzyl-1-(3-nitro-phenyl)-piperidine

There total 1 articles about 4-Benzyl-1-(3-nitro-phenyl)-piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 31252-42-3
4-benzylpyperidine

: 402-67-5
3-fluoro-1-nitrobenzene

: 831203-53-3
4-benzyl-1-(3-nitrophenyl)piperidine

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 90 ℃; for 24h;
DOI:10.1021/jm050765n

Reference yield: 100.0%

: 831203-53-3
4-benzyl-1-(3-nitrophenyl)piperidine

: 478403-42-8
3-(4-benzylpiperidin-1-yl)phenylamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; at 20 ℃; for 8h; under 2585.74 Torr;
DOI:10.1021/jm050765n

Reference yield:

: 831203-53-3
4-benzyl-1-(3-nitrophenyl)piperidine

: 5-nitro-furan-2-carboxylic acid [3-(4-benzyl-piperidin-1-yl)-phenyl]-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / H₂ / Pd/C / ethyl acetate; methanol / 8 h / 20 °C / 2585.74 Torr

2: 96 percent / Et₃N / CH₂Cl₂ / 12 h / 20 °C

With hydrogen; triethylamine; palladium on activated charcoal; In methanol; dichloromethane; ethyl acetate;
DOI:10.1021/jm050765n