Phosphinous acid, diphenyl-, 4-methylphenyl ester

Base Information

• Chemical Name: Phosphinous acid, diphenyl-, 4-methylphenyl ester
• CAS No.: 83128-15-8
• Molecular Formula: C19H17OP
• Molecular Weight: 292.317
• Mol file: 83128-15-8.mol

Synonyms:

Chemical Property of Phosphinous acid, diphenyl-, 4-methylphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phosphinous acid, diphenyl-, 4-methylphenyl ester

There total 1 articles about Phosphinous acid, diphenyl-, 4-methylphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

p-cresol (106-44-5) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → p-tolyl diphenylphosphinite (83128-15-8)

Guidance literature:

With triethylamine; In toluene; for 18h; Heating;

DOI:10.1039/b303657j

Reference yield: 84.0%

acetylacetonatodicarbonylrhodium(l) + p-tolyl diphenylphosphinite (83128-15-8) → Rh(CH3COCHCOCH3)CO(Ph2POPh-p-CH3)

Guidance literature:

In hexane; for 0.25h; Schlenk technique;

DOI:10.1016/j.poly.2015.12.015

Reference yield: 82.4%

1-Nitropropen (3156-70-5) + p-tolyl diphenylphosphinite (83128-15-8) → p-cresol (106-44-5) + 4-methyl-o-phenyl phenyl(phenyl)phosphinate (21713-53-1) + (1-cyanoethyl)diphenylphosphine oxide

Guidance literature:

In diethyl ether; at 30 - 35 ℃; for 1h;

upstream raw materials:

p-cresol

chloro-diphenylphosphine

Downstream raw materials:

p-cresol

4-methyl-o-phenyl phenyl(phenyl)phosphinate

[(Pd(μ-Cl)(κ2-P,C-PPh2(OC6H3-4-Me)))2]

diphenyl(p-tolyl)phosphine oxide

Refernces

• 1、 Bedford, Robin B.,Hazelwood, Samantha L. Welch,Horton, Peter N.,Hursthouse, Michael B.. "Orthopalladated phosphinite complexes as high-activity catalysts for the suzuki reaction". . p. 4164 - 4174. Retrieved 2007/10/03.