2-(2,2-Dimethyl-1,3-dioxolan-4-yl)acetaldehyde

Base Information

• Chemical Name: 2-(2,2-Dimethyl-1,3-dioxolan-4-yl)acetaldehyde
• CAS No.: 83141-42-8
• Molecular Formula: C7H12O3
• Molecular Weight: 144.17
• European Community (EC) Number: 845-008-2
• DSSTox Substance ID: DTXSID20450740
• Nikkaji Number: J845.173G
• Mol file: 83141-42-8.mol

Synonyms:2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde;83141-42-8;SCHEMBL899349;DTXSID20450740;BASUVKNKERZYGZ-UHFFFAOYSA-N;AKOS006229728;2,2-Dimethyl-1,3-dioxolane-4-ethanal;2,2-dimethyl-1,3-dioxolane-4-acetaldehyde;FT-0695391;EN300-1428645

Chemical Property of 2-(2,2-Dimethyl-1,3-dioxolan-4-yl)acetaldehyde

Chemical Property:

• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 144.078644241
• Heavy Atom Count: 10
• Complexity: 131

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(OCC(O1)CC=O)C

Technology Process of 2-(2,2-Dimethyl-1,3-dioxolan-4-yl)acetaldehyde

There total 1 articles about 2-(2,2-Dimethyl-1,3-dioxolan-4-yl)acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethyl-4-vinyl-1,3-dioxolane (83968-02-9) → 1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanone (161972-09-4) + 2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde (83141-42-8)

Guidance literature:

With bis(benzonitrile)palladium(II) dichloride; copper(II) choride dihydrate; oxygen; sodium nitrite; In nitromethane; tert-butyl alcohol; at 20 - 25 ℃; for 4h; under 760.051 Torr;

DOI:10.1021/ja411749k

Reference yield: 82.0%

2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde (83141-42-8) + (4-benzyloxyphenyl)methyl triphenylphosphonium bromide → O-isopropylidene-1-(4'-benzyloxyphenyl)-1-pentene-4,5-diol (869005-53-8)

Guidance literature:

(4-benzyloxyphenyl)methyl triphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.166667h;

2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde; In tetrahydrofuran; at 20 ℃; for 10h;

DOI:10.1002/jhet.5570420614

Reference yield: 76.0%

benzyltriphenylphosphonium bromide (1449-46-3) + 2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde (83141-42-8) → O-isopropylidene-1-phenyl-1-pentene-4,5-diol (869005-56-1)

Guidance literature:

benzyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.166667h;

2-(2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde; In tetrahydrofuran; at 20 ℃; for 10h;

DOI:10.1002/jhet.5570420614

upstream raw materials:

2,2-dimethyl-4-vinyl-1,3-dioxolane

Downstream raw materials:

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

2,2-dimethyl-1,3-dithiane

2-<2,3-(isopropylidenedioxy)propyl>-1,3-dithiane

2-(2',3'-dihydroxypropyl-1')-1,3-dithiane