6-Methyl-2-pyridinecarbaldehyde oxime

Base Information

Chemical Name:6-Methyl-2-pyridinecarbaldehyde oxime
CAS No.:1195-40-0
Molecular Formula:C₇H₈N₂O
Molecular Weight:136.153
Hs Code.:
DSSTox Substance ID:DTXSID701267591
Mol file:1195-40-0.mol

Synonyms:6-methylpyridine-2-aldoxime;SCHEMBL68179;DTXSID701267591;6-methyl-2-pyridinecarbaldehyde oxime;2-Pyridinecarboxaldehyde, 6-methyl-, oxime

Suppliers and Price of 6-Methyl-2-pyridinecarbaldehyde oxime

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Methylpyridine-2-carbaldehydeOxime
500mg
$ 310.00

Matrix Scientific
6-Methylpyridine-2-carbaldehyde oxime
1g
$ 400.00

Matrix Scientific
6-Methylpyridine-2-carbaldehyde oxime
0.500g
$ 320.00

Labseeker
6-METHYL-2-PYRIDINEALDOXIME 95
25g
$ 2750.00

Labseeker
6-METHYL-2-PYRIDINEALDOXIME 95
5g
$ 1333.00

Total 12 raw suppliers

Chemical Property of 6-Methyl-2-pyridinecarbaldehyde oxime

Chemical Property:

Vapor Pressure:0.188mmHg at 25°C
Boiling Point:210.9°Cat760mmHg
Flash Point:81.4°C
PSA：45.48000
Density:1.11g/cm³
LogP:1.19810
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:136.063662883
Heavy Atom Count:10
Complexity:125

Purity/Quality:

97% ^*data from raw suppliers

6-Methylpyridine-2-carbaldehydeOxime ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=CC=C1)C=NO

Technology Process of 6-Methyl-2-pyridinecarbaldehyde oxime

There total 5 articles about 6-Methyl-2-pyridinecarbaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1122-72-1
6-methyl-2-pyridinecarboxaldehyde

: 1265324-16-0,1195-40-0
(E)-6-(methyl)picolinaldehyde oxime

Guidance literature:: With hydroxylamine hydrochloride; potassium carbonate; In ethanol; water; for 0.5h; Reflux;

Reference yield:

: 108-48-5
2,6-dimethylpyridine

: 1265324-16-0,1195-40-0
(E)-6-(methyl)picolinaldehyde oxime

Guidance literature:: Multi-step reaction with 4 steps

1.1: 2,2,2-Trifluoroacetophenone; dihydrogen peroxide; potassium carbonate / tert-butyl alcohol; acetonitrile; water / 28 h / 23 °C

2.1: trifluoroacetic anhydride / dichloromethane / 42 h / 23 °C / Inert atmosphere

2.2: 3 h / 0 - 23 °C / Inert atmosphere

3.1: manganese(IV) oxide / 1,2-dichloro-ethane / 22 h / Inert atmosphere; Reflux

4.1: hydroxylamine hydrochloride; potassium carbonate / water; methanol / 3 h / Reflux

With manganese(IV) oxide; 2,2,2-Trifluoroacetophenone; hydroxylamine hydrochloride; dihydrogen peroxide; potassium carbonate; trifluoroacetic anhydride; In methanol; dichloromethane; water; 1,2-dichloro-ethane; acetonitrile; tert-butyl alcohol;

Reference yield:

: 1073-23-0
2,6-lutidine N-oxide

: 1265324-16-0,1195-40-0
(E)-6-(methyl)picolinaldehyde oxime

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic anhydride / dichloromethane / 48 h / 23 °C / Inert atmosphere; Schlenk technique

2: manganese(IV) oxide / 1,2-dichloro-ethane / 22 h / Inert atmosphere; Schlenk technique; Reflux

3: potassium carbonate; hydroxylamine hydrochloride / water; methanol / 3 h / Reflux

With manganese(IV) oxide; hydroxylamine hydrochloride; potassium carbonate; trifluoroacetic anhydride; In methanol; dichloromethane; water; 1,2-dichloro-ethane;
DOI:10.1021/acsmedchemlett.9b00586