(R)-1-benzyl-3-phenylpiperazine

Base Information

• Chemical Name: (R)-1-benzyl-3-phenylpiperazine
• CAS No.: 832155-10-9
• Molecular Formula: C17H20N2
• Molecular Weight: 252.359
• Mol file: 832155-10-9.mol

Synonyms:(R)-N4-BENZYL-2-PHENYLPIPERAZINE;(R)-1-benzyl-3-phenylpiperazine;

Chemical Property of (R)-1-benzyl-3-phenylpiperazine

Chemical Property:

• PSA: 15.27000
• Density: 1.069
• LogP: 3.09980

Purity/Quality:

97% ^*data from raw suppliers

(R)-N-4-BENZYL-2-PHENYLPIPERAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-1-benzyl-3-phenylpiperazine

There total 2 articles about (R)-1-benzyl-3-phenylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-2-phenyl-4-(phenylmethyl)-1-(2-propenyl)hexahydropyrazine dihydrochloride → (R)-3-phenyl-1-(phenylmethyl)hexahydropyrazine (832155-10-9,502482-38-4)

Guidance literature:

(R)-2-phenyl-4-(phenylmethyl)-1-(2-propenyl)hexahydropyrazine dihydrochloride; ruthenium trichloride; In water; at 100 ℃; for 24h;

With sodium hydroxide; In water; toluene;

Reference yield:

C17H15N2(1+)*Br(1-) → (R)-3-phenyl-1-(phenylmethyl)hexahydropyrazine (832155-10-9,502482-38-4) + (S)-1-benzyl-3-phenylpiperazine (502482-38-4)

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; (2S)-1-[(1S)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene; hydrogen; In toluene; at -20 - 20 ℃; for 36h; under 62059.4 Torr; Reagent/catalyst; Solvent; Temperature; Pressure; enantioselective reaction;

DOI:10.1021/acs.orglett.6b01190