3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid

Base Information

Chemical Name:3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid
CAS No.:83249-10-9
Molecular Formula:C8H10O4
Molecular Weight:170.165
Hs Code.:2917198090
European Community (EC) Number:810-718-3
Nikkaji Number:J516.178I
Mol file:83249-10-9.mol

Synonyms:83249-10-9;3-(methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid;3-methoxycarbonylbicyclo[1.1.1]pentane-1-carboxylic acid;Bicyclo[1.1.1]pentane-1,3-dicarboxylic acid monoMethyl ester;MFCD20638314;3-Methoxycarbonylbicyclo-[1.1.1]pentane-1-carboxylic acid;SCHEMBL9143861;SCHEMBL20851067;SCHEMBL20851079;UJZHYIMESNWEQA-UHFFFAOYSA-N;AMY12281;AKOS024255979;CS-W001056;GS-8008;SB38921;SY042099;M3149;EN300-132008;EN300-19052195;Z1262511436;3-(methoxycarbonyl)bicyclo<1.1.1>pentane-1-carboxylic acid;3-(methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylicacid;Bicyclo[1.1.1]pentane-1,3-dicarboxylic acid, 1-methyl ester;Bicyclo[1.1.1]pentane-1,3-dicarboxylic acid, 1-methyl ester, AldrichCPR

Suppliers and Price of 3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Bicyclo[1.1.1]pentane-1,3-dicarboxylicAcid,1-methylEster
250mg
$ 875.00

TRC
Bicyclo[1.1.1]pentane-1,3-dicarboxylicAcid,1-methylEster
5mg
$ 50.00

TCI Chemical
3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic Acid
200MG
$ 166.00

TCI Chemical
3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic Acid
1G
$ 497.00

SynQuest Laboratories
3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid 97.0%
1 g
$ 890.00

Oakwood
3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid
250mg
$ 35.00

Oakwood
3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid
1g
$ 70.00

Matrix Scientific
3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic Acid 97.0%
1g
$ 530.00

J&W Pharmlab
Bicyclo[1.1.1]pentane-1,3-dicarboxylicacidmonomethylester 96%
1g
$ 398.00

J&W Pharmlab
Bicyclo[1.1.1]pentane-1,3-dicarboxylicacidmonomethylester 96%
5g
$ 1590.00

Total 35 raw suppliers

Chemical Property of 3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid

Chemical Property:

Melting Point:138-139 °C(Solv: chloroform (67-66-3); heptane (142-82-5))
Boiling Point:272.2±40.0 °C(Predicted)
PKA:4.50±0.40(Predicted)
PSA：66.43000
Density:1.559±0.06 g/cm3(Predicted)
LogP:-0.92040
Storage Temp.:2-8°C
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:170.05790880
Heavy Atom Count:12
Complexity:249

Purity/Quality:

99%, ^*data from raw suppliers

Bicyclo[1.1.1]pentane-1,3-dicarboxylicAcid,1-methylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C12CC(C1)(C2)C(=O)O
Uses Bicyclo[1.1.1]pentane-1,3-dicarboxylic Acid, 1-methyl Ester acts as a reagent for the synthesis and in the biopharmaceutical evaluation of imatinib analogs. Also functions as a reagent for the preparation and in biological evaluation of novel bicyclo[1.1.1]pentane-based acidic amino acids as glutamate receptors ligands It is a COVID19-related research product.

Technology Process of 3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid

There total 14 articles about 3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 115913-32-1
dimethyl bicyclo<1.1.1>pentane-1,3-dicarboxylate

: 83249-10-9
3‐(methoxycarbonyl)bicyclo[1.1.1]pentane‐1‐carboxylic acid

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; at 50 ℃; for 72h;
DOI:10.1021/acs.joc.1c00977

Reference yield: 63.0%

: 5781-53-3
monomethyl oxalyl chloride

: 35634-10-7
[1.1.1]propellane

: 83249-10-9
3‐(methoxycarbonyl)bicyclo[1.1.1]pentane‐1‐carboxylic acid

Guidance literature:: monomethyl oxalyl chloride; [1.1.1]propellane; In diethyl ether; at -80 - 0 ℃;

With water; for 2h; Alkaline conditions;