Piperidine, 4-azido-1-(phenylmethyl)-

Base Information

Chemical Name:Piperidine, 4-azido-1-(phenylmethyl)-
CAS No.:832684-07-8
Molecular Formula:C12H16N4
Molecular Weight:216.286
Hs Code.:
DSSTox Substance ID:DTXSID50459084
Nikkaji Number:J2.120.161H

Synonyms:Piperidine, 4-azido-1-(phenylmethyl)-;832684-07-8;1-Benzyl-4-azidopiperidine;DTXSID50459084

Suppliers and Price of Piperidine, 4-azido-1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Piperidine, 4-azido-1-(phenylmethyl)-

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:216.137496527
Heavy Atom Count:16
Complexity:246

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1N=[N+]=[N-])CC2=CC=CC=C2

Technology Process of Piperidine, 4-azido-1-(phenylmethyl)-

There total 3 articles about Piperidine, 4-azido-1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 4727-72-4
1-benzyl-4-hydroxypiperidine

: 832684-07-8
4-azido-1-(phenylmethyl)piperidine

Guidance literature:: With nicotinoyl azide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1055/s-2004-831254

Reference yield: 66.0%

: 101768-14-3
1-benzyl-4-piperidinyl 4-methylbenzenesulfonate

: 832684-07-8
4-azido-1-(phenylmethyl)piperidine

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 90 ℃; for 15h; Inert atmosphere;
DOI:10.1080/00397911.2020.1776876

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 832684-07-8
4-azido-1-(phenylmethyl)piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate / methanol / 20 °C / Inert atmosphere

2: triethylamine; dmap / dichloromethane / 14 h / 0 - 20 °C / Inert atmosphere

3: sodium azide / N,N-dimethyl-formamide / 15 h / 90 °C / Inert atmosphere

With dmap; sodium tetrahydroborate; sodium azide; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1080/00397911.2020.1776876