2-[Bis(4-methoxyphenyl)methylidene]butanedioic acid

Base Information

• Chemical Name: 2-[Bis(4-methoxyphenyl)methylidene]butanedioic acid
• CAS No.: 40938-16-7
• Molecular Formula: C19H18O6
• Molecular Weight: 342.3426
• NSC Number: 113023
• DSSTox Substance ID: DTXSID60296987
• Mol file: 40938-16-7.mol

Synonyms:2-[bis(4-methoxyphenyl)methylidene]butanedioic acid;40938-16-7;NSC113023;DTXSID60296987;NSC-113023;A825485

Chemical Property of 2-[Bis(4-methoxyphenyl)methylidene]butanedioic acid

Chemical Property:

• Vapor Pressure: 4.42E-12mmHg at 25°C
• Boiling Point: 530.4°Cat760mmHg
• Flash Point: 189.8°C
• Density: 1.282g/cm³
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 342.11033829
• Heavy Atom Count: 25
• Complexity: 470

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=C(CC(=O)O)C(=O)O)C2=CC=C(C=C2)OC

Technology Process of 2-[Bis(4-methoxyphenyl)methylidene]butanedioic acid

There total 5 articles about 2-[Bis(4-methoxyphenyl)methylidene]butanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H26O6 → (4,4'-dimethoxy-benzhydrylidene)-succinic acid (40938-16-7)

Guidance literature:

C₂₃H₂₆O₆; With water; sodium hydroxide; In tert-butyl alcohol;

With hydrogenchloride; In water;

DOI:10.2174/1570180812666150529204508

Reference yield:

bis(p-methoxyphenyl)methanone (90-96-0) + succinic acid diethyl ester (123-25-1) → (4,4'-dimethoxy-benzhydrylidene)-succinic acid (40938-16-7)

Guidance literature:

With potassium tert-butylate; tert-butyl alcohol; Erwaermen des Reaktionsprodukts mit wss.-aethanol. KOH;

Reference yield:

(4,4'-dimethoxy-benzhydrylidene)-succinic acid-1-tert-butyl ester (883836-83-7) → (4,4'-dimethoxy-benzhydrylidene)-succinic acid (40938-16-7)

Guidance literature:

With barium dihydroxide; at 150 ℃; unter Druck;

DOI:10.1021/jo01108a616

upstream raw materials:

(4,4'-dimethoxy-benzhydrylidene)-succinic acid-1-tert-butyl ester

bis(p-methoxyphenyl)methanone

succinic acid diethyl ester

4,4'-Dihydroxybenzophenone

Downstream raw materials:

(4,4'-dimethoxy-benzhydrylidene)-succinic acid anhydride

4,4-bis-(4-methoxy-phenyl)-but-3-enoic acid

4,4’-(propa-1,2-diene-1,1-diyl)bis(methoxybenzene)

4,4-bis(4-methoxyphenyl)-4-butyrolactone