N-2-Acetylamino-7-iodofluorene

Base Information

• Chemical Name: N-2-Acetylamino-7-iodofluorene
• CAS No.: 43146-78-7
• Molecular Formula: C₁₅H₁₂INO
• Molecular Weight: 349.171
• Hs Code.: 2924299090
• European Community (EC) Number: 668-240-4
• NSC Number: 9863
• DSSTox Substance ID: DTXSID90962926
• Nikkaji Number: J832.962A
• Wikidata: Q82944719
• ChEMBL ID: CHEMBL84444
• Mol file: 43146-78-7.mol

Synonyms:7-iodo-2-fluorenylacetamide;7-iodo-N-2-acetylaminofluorene;N-2-acetylamino-7-iodofluorene

Chemical Property of N-2-Acetylamino-7-iodofluorene

Chemical Property:

• Vapor Pressure: 2.08E-11mmHg at 25°C
• Boiling Point: 532.2°Cat760mmHg
• Flash Point: 275.7°C
• PSA: 29.10000
• Density: 1.715g/cm³
• LogP: 3.89380
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 348.99636
• Heavy Atom Count: 18
• Complexity: 333

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-ACETAMIDO-7-IODOFLUORENE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC1=CC2=C(C=C1)C3=C(C2)C=C(C=C3)I

Technology Process of N-2-Acetylamino-7-iodofluorene

There total 4 articles about N-2-Acetylamino-7-iodofluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetylaminofluorene (53-96-3) → 7-Jod-2-acetamino-fluoren (43146-78-7)

Guidance literature:

With chloroform; steareth-10; anschliessendes Erhitzen mit NaHSO₃ in Essigsaeure;

DOI:10.1021/ja01160a098

Reference yield:

2-nitro-7-iodo-9H-fluorene (23055-47-2) → 7-Jod-2-acetamino-fluoren (43146-78-7)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc; CaCl₂; aq.-ethanolic acetic acid

With acetic acid; calcium chloride; zinc;

DOI:10.1021/ja01160a098

Reference yield:

7-iodo-9H-fluorene-2-amine (34172-48-0) + acetic anhydride (108-24-7) → 7-Jod-2-acetamino-fluoren (43146-78-7)

Guidance literature:

DOI:10.1021/ja01160a098

upstream raw materials:

2-acetylaminofluorene

7-iodo-9H-fluorene-2-amine

acetic anhydride

2-nitro-7-iodo-9H-fluorene